285274

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1726301..1726866 Replicon chromosome
Accession NZ_HG992742
Organism Vibrio sp. B1ASS3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KJB05_RS08170 Protein ID WP_182020508.1
Coordinates 1726579..1726866 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U3BLE1
Locus tag KJB05_RS08165 Protein ID WP_000086647.1
Coordinates 1726301..1726582 (+) Length 94 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJB05_RS08130 1722194..1722283 + 90 WP_244142900.1 DUF3265 domain-containing protein -
KJB05_RS08135 (ACOMICROBIO_NCLOACGD_01626) 1722754..1723356 + 603 WP_208444461.1 hypothetical protein -
KJB05_RS28605 1723720..1724211 + 492 Protein_1544 ATP-binding protein -
KJB05_RS08145 (ACOMICROBIO_NCLOACGD_01628) 1724430..1725542 + 1113 WP_208444459.1 DUF4236 domain-containing protein -
KJB05_RS08150 1725557..1725649 + 93 WP_005445734.1 DUF3265 domain-containing protein -
KJB05_RS08155 (ACOMICROBIO_LOCUS1072) 1725682..1726086 + 405 WP_244142897.1 hydrolase -
KJB05_RS08160 1726121..1726210 + 90 WP_072828858.1 DUF3265 domain-containing protein -
KJB05_RS08165 (ACOMICROBIO_LOCUS1073) 1726301..1726582 + 282 WP_000086647.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KJB05_RS08170 (ACOMICROBIO_NCLOACGD_01631) 1726579..1726866 + 288 WP_182020508.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KJB05_RS08175 (ACOMICROBIO_LOCUS1074) 1727018..1727476 + 459 WP_038898338.1 GNAT family N-acetyltransferase -
KJB05_RS28610 1727454..1727573 + 120 WP_244142899.1 DUF3265 domain-containing protein -
KJB05_RS08180 (ACOMICROBIO_NCLOACGD_01633) 1727577..1727966 + 390 WP_208444457.1 MAPEG family protein -
KJB05_RS08185 (ACOMICROBIO_NCLOACGD_01634) 1728044..1728274 - 231 WP_005442035.1 PAS factor family protein -
KJB05_RS08190 (ACOMICROBIO_LOCUS1075) 1728696..1729094 - 399 WP_080641587.1 helix-turn-helix domain-containing protein -
KJB05_RS08195 (ACOMICROBIO_NCLOACGD_01636) 1729235..1729714 + 480 WP_208444456.1 ester cyclase -
KJB05_RS08200 (ACOMICROBIO_LOCUS1076) 1729830..1730492 + 663 WP_208444455.1 peptidase E -
KJB05_RS08205 (ACOMICROBIO_NCLOACGD_01638) 1730575..1730991 + 417 WP_244868319.1 tetratricopeptide repeat protein -
KJB05_RS08210 (ACOMICROBIO_NCLOACGD_01640) 1731477..1731845 + 369 WP_208444453.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island fos - 1630141..1726866 96725
- flank IS/Tn - - 1721075..1722085 1010
- inside Integron - - 1714014..1726582 12568


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 11017.67 Da        Isoelectric Point: 5.1098

>T285274 WP_182020508.1 NZ_HG992742:1726579-1726866 [Vibrio sp. B1ASS3]
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRVIYSLSHEIRV
LTVRNCRQILSEDDV

Download         Length: 288 bp


Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10398.91 Da        Isoelectric Point: 5.8650

>AT285274 WP_000086647.1 NZ_HG992742:1726301-1726582 [Vibrio sp. B1ASS3]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK

Download         Length: 282 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A4P8G0X0

References