Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 31764..33283 | Replicon | plasmid pOSCIL6304.01 |
| Accession | NC_019700 | ||
| Organism | Oscillatoria acuminata PCC 6304 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | K9TTJ0 |
| Locus tag | OSCIL6304_RS29955 | Protein ID | WP_015163275.1 |
| Coordinates | 32366..33283 (+) | Length | 306 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | K9TSG3 |
| Locus tag | OSCIL6304_RS29950 | Protein ID | WP_015163274.1 |
| Coordinates | 31764..32369 (+) | Length | 202 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OSCIL6304_RS34950 | 29653..29817 | + | 165 | WP_015163271.1 | hypothetical protein | - |
| OSCIL6304_RS34955 | 30062..30178 | + | 117 | Protein_31 | ParA family protein | - |
| OSCIL6304_RS34960 | 30355..30597 | + | 243 | WP_044198676.1 | hypothetical protein | - |
| OSCIL6304_RS34965 | 31280..31501 | + | 222 | WP_044198635.1 | hypothetical protein | - |
| OSCIL6304_RS29950 | 31764..32369 | + | 606 | WP_015163274.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
| OSCIL6304_RS29955 | 32366..33283 | + | 918 | WP_015163275.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| OSCIL6304_RS29960 | 33384..33833 | - | 450 | WP_015163276.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..64128 | 64128 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 306 a.a. Molecular weight: 35046.95 Da Isoelectric Point: 8.2285
>T28527 WP_015163275.1 NC_019700:32366-33283 [Oscillatoria acuminata PCC 6304]
MTKPKRNLAASVHQKLLNFSKEQKDDFQSVLTRYALERFLYRLSQSPYQNQYILKGALLFSIWSDETHRPTRDLDLLGYG
QTEISHLEQIFREICLTQVEPDGLEFKADEVAGSRIKENQQYEGVRIRFRAFLSGTNTRTDLQIDIGFGDAVTPKAMEVE
FPTILEQFPAPSLRAYPPETVIAEKFQAMVKLGIANSRLKDFYDIWFLCHNFEFKGPEIYLAIQATFGRRNTPLPQEIPS
AFSAQFSQIKLKDWNAFISKNKLATNGASFNNVLSKLENFLMPPCSAAAKGEVFNKTWRQSGYWE
MTKPKRNLAASVHQKLLNFSKEQKDDFQSVLTRYALERFLYRLSQSPYQNQYILKGALLFSIWSDETHRPTRDLDLLGYG
QTEISHLEQIFREICLTQVEPDGLEFKADEVAGSRIKENQQYEGVRIRFRAFLSGTNTRTDLQIDIGFGDAVTPKAMEVE
FPTILEQFPAPSLRAYPPETVIAEKFQAMVKLGIANSRLKDFYDIWFLCHNFEFKGPEIYLAIQATFGRRNTPLPQEIPS
AFSAQFSQIKLKDWNAFISKNKLATNGASFNNVLSKLENFLMPPCSAAAKGEVFNKTWRQSGYWE
Download Length: 918 bp
>T28527 NC_019700:32366-33283 [Oscillatoria acuminata PCC 6304]
ATGACGAAGCCCAAACGCAACCTAGCTGCCTCTGTTCATCAGAAACTATTAAATTTTTCTAAGGAGCAAAAGGATGACTT
CCAATCAGTTCTAACCCGGTATGCTTTGGAGCGTTTTTTGTACCGTTTGAGCCAATCGCCCTATCAAAATCAATACATCC
TTAAAGGGGCATTACTTTTTTCGATTTGGAGCGACGAAACGCATCGACCGACGCGAGACTTGGATTTACTAGGTTATGGC
CAGACAGAAATTTCTCATTTAGAGCAAATCTTCCGAGAGATTTGTCTGACTCAGGTAGAGCCAGATGGTCTTGAGTTTAA
GGCGGATGAGGTAGCCGGTTCAAGAATCAAAGAAAACCAGCAGTATGAAGGGGTAAGAATTAGGTTTCGGGCGTTTTTGT
CAGGGACTAATACTCGCACCGACCTTCAGATTGACATTGGCTTTGGAGATGCGGTGACGCCCAAAGCAATGGAGGTAGAA
TTTCCGACAATTTTAGAACAATTTCCAGCGCCATCTCTGCGGGCTTACCCTCCGGAAACGGTGATAGCTGAGAAATTTCA
AGCAATGGTTAAATTAGGCATAGCCAATAGTCGCCTGAAAGATTTTTATGATATCTGGTTTCTTTGCCACAATTTCGAGT
TTAAAGGACCGGAAATTTATTTGGCTATTCAGGCTACGTTTGGACGACGTAATACACCGCTCCCTCAAGAAATTCCTTCC
GCCTTTTCCGCTCAATTCTCTCAAATAAAACTAAAGGATTGGAATGCTTTTATTTCCAAAAACAAGCTCGCTACAAACGG
GGCCAGCTTTAATAATGTACTTTCAAAGTTAGAAAATTTTCTGATGCCGCCATGTTCAGCGGCAGCCAAGGGGGAGGTAT
TTAACAAGACGTGGCGTCAATCCGGTTATTGGGAGTAA
ATGACGAAGCCCAAACGCAACCTAGCTGCCTCTGTTCATCAGAAACTATTAAATTTTTCTAAGGAGCAAAAGGATGACTT
CCAATCAGTTCTAACCCGGTATGCTTTGGAGCGTTTTTTGTACCGTTTGAGCCAATCGCCCTATCAAAATCAATACATCC
TTAAAGGGGCATTACTTTTTTCGATTTGGAGCGACGAAACGCATCGACCGACGCGAGACTTGGATTTACTAGGTTATGGC
CAGACAGAAATTTCTCATTTAGAGCAAATCTTCCGAGAGATTTGTCTGACTCAGGTAGAGCCAGATGGTCTTGAGTTTAA
GGCGGATGAGGTAGCCGGTTCAAGAATCAAAGAAAACCAGCAGTATGAAGGGGTAAGAATTAGGTTTCGGGCGTTTTTGT
CAGGGACTAATACTCGCACCGACCTTCAGATTGACATTGGCTTTGGAGATGCGGTGACGCCCAAAGCAATGGAGGTAGAA
TTTCCGACAATTTTAGAACAATTTCCAGCGCCATCTCTGCGGGCTTACCCTCCGGAAACGGTGATAGCTGAGAAATTTCA
AGCAATGGTTAAATTAGGCATAGCCAATAGTCGCCTGAAAGATTTTTATGATATCTGGTTTCTTTGCCACAATTTCGAGT
TTAAAGGACCGGAAATTTATTTGGCTATTCAGGCTACGTTTGGACGACGTAATACACCGCTCCCTCAAGAAATTCCTTCC
GCCTTTTCCGCTCAATTCTCTCAAATAAAACTAAAGGATTGGAATGCTTTTATTTCCAAAAACAAGCTCGCTACAAACGG
GGCCAGCTTTAATAATGTACTTTCAAAGTTAGAAAATTTTCTGATGCCGCCATGTTCAGCGGCAGCCAAGGGGGAGGTAT
TTAACAAGACGTGGCGTCAATCCGGTTATTGGGAGTAA
Antitoxin
Download Length: 202 a.a. Molecular weight: 22895.44 Da Isoelectric Point: 9.1402
>AT28527 WP_015163274.1 NC_019700:31764-32369 [Oscillatoria acuminata PCC 6304]
MENQSSSKQVLQLARDNQLIRSRDLRARGIHPESVRRLEQQGMLVRAGRGIYTLPQNNLTEHQSQIEACARVPHGIICLL
SALRFHGLTTQAPFEVWMAIANKARPPKDNILPLRIVYMSGKALSEGIEEHDYAGLPVKVYSIAKTVADCFKYRHKLGMD
VALEALRESWNGNRCTIDELWHYAQICRVARVIYPYLESLT
MENQSSSKQVLQLARDNQLIRSRDLRARGIHPESVRRLEQQGMLVRAGRGIYTLPQNNLTEHQSQIEACARVPHGIICLL
SALRFHGLTTQAPFEVWMAIANKARPPKDNILPLRIVYMSGKALSEGIEEHDYAGLPVKVYSIAKTVADCFKYRHKLGMD
VALEALRESWNGNRCTIDELWHYAQICRVARVIYPYLESLT
Download Length: 606 bp
>AT28527 NC_019700:31764-32369 [Oscillatoria acuminata PCC 6304]
ATGGAAAACCAATCTAGCTCAAAGCAGGTGTTGCAACTTGCCCGAGATAACCAGCTTATTCGCTCCCGCGACCTGAGAGC
GCGTGGAATCCATCCCGAGTCTGTGCGGCGACTTGAACAGCAGGGGATGCTGGTCAGGGCAGGGCGTGGAATTTACACGC
TTCCTCAGAATAACCTAACCGAACATCAAAGCCAGATTGAAGCCTGTGCGCGGGTTCCTCATGGGATAATTTGTTTGCTT
TCTGCACTTCGGTTTCATGGACTCACAACCCAGGCTCCTTTTGAAGTCTGGATGGCGATCGCCAACAAAGCACGTCCTCC
AAAAGACAATATTCTCCCTTTGCGGATTGTTTATATGTCAGGCAAAGCTTTGAGTGAAGGCATAGAGGAGCATGACTATG
CGGGGCTGCCGGTGAAAGTCTACAGCATTGCCAAGACAGTCGCAGATTGTTTTAAATACCGCCACAAACTTGGGATGGAC
GTAGCGCTTGAAGCTCTACGGGAATCCTGGAATGGCAATCGCTGCACCATAGATGAACTCTGGCATTATGCTCAAATCTG
TCGCGTAGCTCGCGTTATCTATCCCTACCTAGAATCACTAACATGA
ATGGAAAACCAATCTAGCTCAAAGCAGGTGTTGCAACTTGCCCGAGATAACCAGCTTATTCGCTCCCGCGACCTGAGAGC
GCGTGGAATCCATCCCGAGTCTGTGCGGCGACTTGAACAGCAGGGGATGCTGGTCAGGGCAGGGCGTGGAATTTACACGC
TTCCTCAGAATAACCTAACCGAACATCAAAGCCAGATTGAAGCCTGTGCGCGGGTTCCTCATGGGATAATTTGTTTGCTT
TCTGCACTTCGGTTTCATGGACTCACAACCCAGGCTCCTTTTGAAGTCTGGATGGCGATCGCCAACAAAGCACGTCCTCC
AAAAGACAATATTCTCCCTTTGCGGATTGTTTATATGTCAGGCAAAGCTTTGAGTGAAGGCATAGAGGAGCATGACTATG
CGGGGCTGCCGGTGAAAGTCTACAGCATTGCCAAGACAGTCGCAGATTGTTTTAAATACCGCCACAAACTTGGGATGGAC
GTAGCGCTTGAAGCTCTACGGGAATCCTGGAATGGCAATCGCTGCACCATAGATGAACTCTGGCATTATGCTCAAATCTG
TCGCGTAGCTCGCGTTATCTATCCCTACCTAGAATCACTAACATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|