Detailed information of TA system TA285269

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 1175768..1177115
• Replicon: chromosome
• Accession: NZ_HG992742
• Organism: Vibrio sp. B1ASS3

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: KJB05_RS05450
• Protein ID: WP_208444947.1
• Coordinates: 1176174..1177115 (+)
• Length: 314 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: KJB05_RS05445
• Protein ID: WP_085343578.1
• Coordinates: 1175768..1176172 (+)
• Length: 135 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJB05_RS05430 (ACOMICROBIO_NCLOACGD_01108)	1173433..1173885	-	453	WP_208444948.1	hypothetical protein	-
KJB05_RS05435 (ACOMICROBIO_NCLOACGD_01109)	1174464..1174706	+	243	WP_104036867.1	helix-turn-helix domain-containing protein	-
KJB05_RS05440 (ACOMICROBIO_LOCUS759)	1174986..1175579	+	594	WP_085343577.1	tyrosine-type recombinase/integrase	-
KJB05_RS05445 (ACOMICROBIO_NCLOACGD_01111)	1175768..1176172	+	405	WP_085343578.1	DUF6088 family protein	Antitoxin
KJB05_RS05450 (ACOMICROBIO_NCLOACGD_01112)	1176174..1177115	+	942	WP_208444947.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
KJB05_RS05455 (ACOMICROBIO_LOCUS760)	1177135..1178666	+	1532	Protein_1001	type I restriction-modification system subunit M	-
KJB05_RS05460 (ACOMICROBIO_LOCUS762)	1178656..1179891	+	1236	WP_208444945.1	restriction endonuclease subunit S	-
KJB05_RS05465 (ACOMICROBIO_NCLOACGD_01116)	1179957..1180793	+	837	WP_208444944.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1164401..1180793	16392

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (37-300)

Antitoxin

• Protein of unknown function DUF6088 (7-130)

Sequences

Toxin

Protein

• Length: 314 a.a.
• Molecular weight: 35843.27 Da
• Isoelectric Point: 5.3074

>T285269 WP_208444947.1 NZ_HG992742:1176174-1177115 [Vibrio sp. B1ASS3]
MNTLKQQFLEVSDALELGNPAIIEKDYWVVALLAELAKVCPEHHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNPAFDE
LSRAKKKAARKACVNEIEQAITQSERFTVEARSVRDEYRYVEFELKYPQQFSQAPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYRQPHEVSAFDCVSVYTTLIEKVISMLRRTMSVKRNTERSDDVALVRHIYDVHCITTLSMQELDSIDGLFKAVL
AEDIARFGNQHAEFVANPKQELQLGLKELEENAIFRQRFQEFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI

Nucleotide

• Length: 942 bp

Antitoxin

Protein

• Length: 135 a.a.
• Molecular weight: 15186.50 Da
• Isoelectric Point: 10.5319

>AT285269 WP_085343578.1 NZ_HG992742:1175768-1176172 [Vibrio sp. B1ASS3]
MTAADRIYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALMRE
ILKMKGVDFEMDSLSLQSLSGSSTQIPSSIQYSWDPKQFNRKLVVGSRVLNLPS

Nucleotide

• Length: 405 bp