285259

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4434223..4434592 Replicon chromosome
Accession NZ_HG992337
Organism Xanthomonas arboricola strain 1314c isolate 1314c

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag LOK39_RS18735 Protein ID WP_016904515.1
Coordinates 4434223..4434357 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag LOK39_RS18740 Protein ID WP_006451340.1
Coordinates 4434440..4434592 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOK39_RS18720 (XA1314C_36910) 4431289..4432233 - 945 WP_228600097.1 MBL fold metallo-hydrolase -
LOK39_RS18725 (XA1314C_36920) 4432291..4433580 - 1290 WP_228600098.1 tryptophan--tRNA ligase -
LOK39_RS18730 (XA1314C_36930) 4433763..4433972 - 210 WP_016904514.1 CsbD family protein -
LOK39_RS18735 (XA1314C_36940) 4434223..4434357 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
LOK39_RS18740 (XA1314C_36950) 4434440..4434592 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
LOK39_RS18745 (XA1314C_36960) 4434702..4435625 - 924 WP_167706217.1 arginase -
LOK39_RS18750 (XA1314C_36970) 4436101..4436553 + 453 WP_016904517.1 roadblock/LC7 domain-containing protein -
LOK39_RS18755 (XA1314C_36980) 4436618..4436977 + 360 WP_016904518.1 hypothetical protein -
LOK39_RS18760 (XA1314C_36990) 4437072..4437989 + 918 WP_102251092.1 hypothetical protein -
LOK39_RS18765 (XA1314C_37000) 4437986..4438528 + 543 WP_016904520.1 GTPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T285259 WP_016904515.1 NZ_HG992337:c4434357-4434223 [Xanthomonas arboricola]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT285259 WP_006451340.1 NZ_HG992337:c4434592-4434440 [Xanthomonas arboricola]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0


Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References