285258

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4478705..4479074 Replicon chromosome
Accession NZ_HG992336
Organism Xanthomonas arboricola strain 1311a isolate 1311a

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag LOK40_RS19040 Protein ID WP_016904515.1
Coordinates 4478705..4478839 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag LOK40_RS19045 Protein ID WP_006451340.1
Coordinates 4478922..4479074 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOK40_RS19025 (XA1311A_37200) 4475772..4476716 - 945 WP_065048489.1 MBL fold metallo-hydrolase -
LOK40_RS19030 (XA1311A_37210) 4476774..4478063 - 1290 WP_065048487.1 tryptophan--tRNA ligase -
LOK40_RS19035 (XA1311A_37220) 4478245..4478454 - 210 WP_228607964.1 CsbD family protein -
LOK40_RS19040 (XA1311A_37230) 4478705..4478839 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
LOK40_RS19045 (XA1311A_37240) 4478922..4479074 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
LOK40_RS19050 (XA1311A_37250) 4479184..4480107 - 924 WP_026064823.1 arginase -
LOK40_RS19055 (XA1311A_37260) 4480583..4481035 + 453 WP_228607966.1 roadblock/LC7 domain-containing protein -
LOK40_RS19060 (XA1311A_37270) 4481099..4481458 + 360 WP_016904518.1 hypothetical protein -
LOK40_RS19065 (XA1311A_37280) 4481553..4482470 + 918 WP_127158947.1 hypothetical protein -
LOK40_RS19070 (XA1311A_37290) 4482467..4483009 + 543 WP_016904520.1 GTPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T285258 WP_016904515.1 NZ_HG992336:c4478839-4478705 [Xanthomonas arboricola]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT285258 WP_006451340.1 NZ_HG992336:c4479074-4478922 [Xanthomonas arboricola]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0


Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References