285253

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 1141283..1141842 Replicon chromosome
Accession NZ_HG969192
Organism Bartonella tribocorum strain BM1374166

Toxin (Protein)


Gene name parE Uniprot ID A9IPY8
Locus tag BM1374166_RS04975 Protein ID WP_012231080.1
Coordinates 1141283..1141555 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A5B9CWB1
Locus tag BM1374166_RS04980 Protein ID WP_012231079.1
Coordinates 1141552..1141842 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BM1374166_RS04970 1140137..1141102 - 966 WP_081821882.1 DUF3987 domain-containing protein -
BM1374166_RS04975 1141283..1141555 - 273 WP_012231080.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
BM1374166_RS04980 1141552..1141842 - 291 WP_012231079.1 hypothetical protein Antitoxin
BM1374166_RS12830 1142300..1142449 - 150 WP_169309788.1 hypothetical protein -
BM1374166_RS04985 1142546..1142746 - 201 WP_012231078.1 DNA-binding protein -
BM1374166_RS04990 1142947..1144111 - 1165 Protein_953 integrase arm-type DNA-binding domain-containing protein -
BM1374166_RS04995 1144322..1144945 + 624 WP_012231664.1 DNA adenine methylase -
BM1374166_RS05000 1145456..1145674 + 219 WP_005773872.1 hypothetical protein -
BM1374166_RS05005 1145679..1145951 + 273 WP_012231665.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1013501..1192685 179184


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10612.57 Da        Isoelectric Point: 10.9313

>T285253 WP_012231080.1 NZ_HG969192:c1141555-1141283 [Bartonella tribocorum]
MKLIWTQVARVDRKKIREYISQNNPSAALKFDQLLSEKIEKLVKFSTLGRLGRVVNTREFIVHPNYIMIYDISDGVVRIL
RVLHTKQKFP

Download         Length: 273 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11078.46 Da        Isoelectric Point: 5.2356

>AT285253 WP_012231079.1 NZ_HG969192:c1141842-1141552 [Bartonella tribocorum]
MAETTFTFRVDDVLKNEFSKAAKACDRSGAQLLRDYMRDIVKEQKERSAHDLWFREQVQLGINSANAGDIISSEEIEAEA
KEWRLKIQSKLDRSTL

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A9IPY8

Antitoxin

Source ID Structure
AlphaFold DB A0A5B9CWB1

References