285251

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 563135..563694 Replicon chromosome
Accession NZ_HG969192
Organism Bartonella tribocorum strain BM1374166

Toxin (Protein)


Gene name parE Uniprot ID A9IPY8
Locus tag BM1374166_RS02510 Protein ID WP_012231080.1
Coordinates 563422..563694 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A5B9CWB1
Locus tag BM1374166_RS02505 Protein ID WP_012231079.1
Coordinates 563135..563425 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BM1374166_RS02470 558343..558921 - 579 WP_012231073.1 hypothetical protein -
BM1374166_RS02475 558925..559239 - 315 WP_012231074.1 hypothetical protein -
BM1374166_RS02480 559554..559736 + 183 WP_038473319.1 type II toxin-antitoxin system HicA family toxin -
BM1374166_RS02485 559757..560179 + 423 WP_012231075.1 hypothetical protein -
BM1374166_RS02490 560183..560689 - 507 WP_081458154.1 hypothetical protein -
BM1374166_RS02495 560863..562029 + 1167 WP_012231077.1 site-specific integrase -
BM1374166_RS02500 562230..562430 + 201 WP_012231078.1 DNA-binding protein -
BM1374166_RS12790 562528..562677 + 150 WP_169309786.1 hypothetical protein -
BM1374166_RS02505 563135..563425 + 291 WP_012231079.1 hypothetical protein Antitoxin
BM1374166_RS02510 563422..563694 + 273 WP_012231080.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
BM1374166_RS02515 563941..564843 + 903 Protein_479 DUF3987 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 477153..595130 117977


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10612.57 Da        Isoelectric Point: 10.9313

>T285251 WP_012231080.1 NZ_HG969192:563422-563694 [Bartonella tribocorum]
MKLIWTQVARVDRKKIREYISQNNPSAALKFDQLLSEKIEKLVKFSTLGRLGRVVNTREFIVHPNYIMIYDISDGVVRIL
RVLHTKQKFP

Download         Length: 273 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11078.46 Da        Isoelectric Point: 5.2356

>AT285251 WP_012231079.1 NZ_HG969192:563135-563425 [Bartonella tribocorum]
MAETTFTFRVDDVLKNEFSKAAKACDRSGAQLLRDYMRDIVKEQKERSAHDLWFREQVQLGINSANAGDIISSEEIEAEA
KEWRLKIQSKLDRSTL

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A9IPY8

Antitoxin

Source ID Structure
AlphaFold DB A0A5B9CWB1

References