Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 3813382..3813962 Replicon chromosome
Accession NC_019695
Organism Chroococcidiopsis thermalis PCC 7203

Toxin (Protein)


Gene name mazF Uniprot ID K9U3S3
Locus tag CHRO_RS16765 Protein ID WP_015155424.1
Coordinates 3813382..3813642 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CHRO_RS16770 Protein ID WP_015155425.1
Coordinates 3813636..3813962 (+) Length 109 a.a.

Genomic Context

CHRO_RS16735CHRO_RS16740CHRO_RS16745CHRO_RS16755CHRO_RS16760CHRO_RS16765CHRO_RS16770CHRO_RS16775CHRO_RS16785CHRO_RS16750CHRO_RS16780CHRO_RS16790CHRO_RS16795
Location: 3808534..3809277 (744 bp)
Type: Others
Protein ID: WP_015155418.1
Location: 3809498..3810259 (762 bp)
Type: Others
Protein ID: WP_015155419.1
Location: 3810487..3810960 (474 bp)
Type: Others
Protein ID: WP_015155420.1
Location: 3812238..3812645 (408 bp)
Type: Others
Protein ID: WP_015155422.1
Location: 3812742..3813029 (288 bp)
Type: Others
Protein ID: WP_015155423.1
Location: 3813382..3813642 (261 bp)
Type: Toxin
Protein ID: WP_015155424.1
Location: 3813636..3813962 (327 bp)
Type: Antitoxin
Protein ID: WP_015155425.1
Location: 3813965..3814939 (975 bp)
Type: Others
Protein ID: WP_015155426.1
Location: 3816155..3816721 (567 bp)
Type: Others
Protein ID: WP_015155428.1
Location: 3811074..3811946 (873 bp)
Type: Others
Protein ID: WP_015155421.1
Location: 3814984..3815946 (963 bp)
Type: Others
Protein ID: WP_015155427.1
Location: 3816732..3817268 (537 bp)
Type: Others
Protein ID: WP_015155429.1
Location: 3817371..3818657 (1287 bp)
Type: Others
Protein ID: WP_015155430.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CHRO_RS167353808534..3809277+744WP_015155418.1phycobilisome rod-core linker polypeptide-
CHRO_RS167403809498..3810259+762WP_015155419.1phycobilisome rod-core linker polypeptide-
CHRO_RS167453810487..3810960+474WP_015155420.1hypothetical protein-
CHRO_RS167503811074..3811946-873WP_015155421.1NAD(P)-dependent oxidoreductase-
CHRO_RS167553812238..3812645+408WP_015155422.150S ribosomal protein L21-
CHRO_RS167603812742..3813029+288WP_015155423.150S ribosomal protein L27-
CHRO_RS167653813382..3813642+261WP_015155424.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinToxin
CHRO_RS167703813636..3813962+327WP_015155425.1type II toxin-antitoxin system PemK/MazF family toxinAntitoxin
CHRO_RS167753813965..3814939+975WP_015155426.1XdhC family protein-
CHRO_RS167803814984..3815946-963WP_015155427.1hypothetical protein-
CHRO_RS167853816155..3816721+567WP_015155428.1hypothetical protein-
CHRO_RS167903816732..3817268-537WP_015155429.1bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR-
CHRO_RS167953817371..3818657-1287WP_015155430.1aminopeptidase P N-terminal domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

SpoVT-AbrB domain

(10-45)

Antitoxin

mRNA interferase PemK-like

(1-105)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9841.17 Da        Isoelectric Point: 4.4992

>T28525 WP_015155424.1 NC_019695:3813382-3813642 [Chroococcidiopsis thermalis PCC 7203]
MGTGIRTRIVRIGNSQGIRIPKPLLEQSGIDTEVEIEVQDECLIVRAASRSRIGWDKAFAAMAEQKDDVLLDDVNITEWD
RTEWKW

Download         Length: 261 bp

>T28525 NC_019695:3813382-3813642 [Chroococcidiopsis thermalis PCC 7203]
ATGGGTACGGGTATCAGAACTCGCATTGTCAGAATTGGTAATTCTCAAGGCATCCGCATTCCTAAACCACTATTGGAGCA
AAGTGGTATTGATACAGAAGTAGAGATTGAAGTTCAAGACGAGTGCTTAATTGTGCGTGCAGCATCGCGATCGCGTATCG
GCTGGGATAAAGCATTTGCTGCAATGGCAGAACAAAAAGATGATGTTTTACTTGATGATGTCAATATAACAGAGTGGGAT
CGGACTGAGTGGAAATGGTAG

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12127.23 Da        Isoelectric Point: 9.1569

>AT28525 WP_015155425.1 NC_019695:3813636-3813962 [Chroococcidiopsis thermalis PCC 7203]
MVVKRFDVFLINLHPPTVGSEIQKTRPCVIVSPNEMNQYIATVIVAPMTTKGQPYPTRIACQFQGKDGQIVLDQIRTVDK
TRLVKKLGQINSNEQKAVLDILAEMFAE

Download         Length: 327 bp

>AT28525 NC_019695:3813636-3813962 [Chroococcidiopsis thermalis PCC 7203]
ATGGTAGTTAAGCGTTTTGATGTGTTTCTGATTAACCTCCATCCTCCCACAGTTGGTAGTGAAATTCAAAAAACAAGACC
GTGCGTCATCGTCTCACCAAATGAAATGAATCAGTACATTGCCACTGTTATCGTTGCGCCGATGACAACAAAAGGTCAGC
CGTATCCTACAAGGATCGCTTGCCAGTTTCAAGGTAAAGATGGGCAGATCGTTTTAGACCAAATTCGCACTGTTGATAAA
ACTCGATTGGTCAAAAAACTCGGTCAAATCAATTCCAACGAACAAAAAGCTGTTTTGGATATCCTCGCCGAAATGTTTGC
AGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBK9U3S3

Antitoxin

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Source
ID
Structure
No matching records found

References