Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/-
Location 1881467..1881963 Replicon chromosome
Accession NZ_HG969191
Organism Bartonella henselae strain BM1374165

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag BM1374165_RS09230 Protein ID WP_197536999.1
Coordinates 1881724..1881963 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag BM1374165_RS08205 Protein ID WP_038488683.1
Coordinates 1881467..1881676 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BM1374165_RS08185 1876970..1877470 - 501 Protein_1511 transcriptional regulator -
BM1374165_RS08190 1878119..1878790 - 672 WP_038488679.1 VUT family protein -
BM1374165_RS08195 1878904..1879197 - 294 WP_011181357.1 50S ribosomal protein L28 -
BM1374165_RS08200 1879476..1880261 + 786 WP_011181358.1 SURF1 family protein -
BM1374165_RS08205 1881467..1881676 + 210 WP_038488683.1 hypothetical protein Antitoxin
BM1374165_RS09230 1881724..1881963 + 240 WP_197536999.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BM1374165_RS09560 1882189..1882345 + 157 Protein_1517 DUF4102 domain-containing protein -
BM1374165_RS09235 1884029..1884184 - 156 WP_011181359.1 DUF1127 domain-containing protein -
BM1374165_RS08215 1884465..1886081 - 1617 WP_011181360.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-75)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9317.94 Da        Isoelectric Point: 10.0545

>T285243 WP_197536999.1 NZ_HG969191:1881724-1881963 [Bartonella henselae]
ILSYIARENPFAARRMKKQLEASVLPLSEHPYLYQKSERVLKLREIVAHPNYLILYQVTVNQIEIVTVVHTRREFPVSL

Download         Length: 240 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7989.02 Da        Isoelectric Point: 4.4593

>AT285243 WP_038488683.1 NZ_HG969191:1881467-1881676 [Bartonella henselae]
IHDKYKGKTAFSLLVSEFEIAEQELSYTDWLRNKVAKSFANLHPVIPHDEVMAEMEAVRDQIVAEQEEL

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References