Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/-
Location 1811329..1811825 Replicon chromosome
Accession NZ_HG965802
Organism Bartonella henselae strain BM1374163

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag PRJBM_RS08875 Protein ID WP_197537104.1
Coordinates 1811586..1811825 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag PRJBM_RS07845 Protein ID WP_034448465.1
Coordinates 1811329..1811538 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRJBM_RS07825 1806830..1807330 - 501 Protein_1448 transcriptional regulator -
PRJBM_RS07830 1807979..1808650 - 672 WP_011181356.1 VUT family protein -
PRJBM_RS07835 1808764..1809057 - 294 WP_011181357.1 50S ribosomal protein L28 -
PRJBM_RS07840 1809336..1810121 + 786 WP_011181358.1 SURF1 family protein -
PRJBM_RS07845 1811329..1811538 + 210 WP_034448465.1 hypothetical protein Antitoxin
PRJBM_RS08875 1811586..1811825 + 240 WP_197537104.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PRJBM_RS09265 1812051..1812207 + 157 Protein_1454 DUF4102 domain-containing protein -
PRJBM_RS08880 1813892..1814047 - 156 WP_011181359.1 DUF1127 domain-containing protein -
PRJBM_RS07855 1814328..1815944 - 1617 WP_011181360.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-75)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9299.91 Da        Isoelectric Point: 10.0545

>T285227 WP_197537104.1 NZ_HG965802:1811586-1811825 [Bartonella henselae]
ILSYIARENPFAARRIKKQLEASVLPLSEHPYLYQKSERVLKLREIVAHPNYLILYQVTVNQIEIVTVVHTRREFPVSL

Download         Length: 240 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7954.96 Da        Isoelectric Point: 4.3201

>AT285227 WP_034448465.1 NZ_HG965802:1811329-1811538 [Bartonella henselae]
IHDQYKGKTAFSLLVSEFEIAEQELSYTDWLRNKVAKSLANLHPVIPHDEVMAEMEAVRDQIVAEQEEL

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References