Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 5005981..5006801 Replicon chromosome
Accession NZ_HG941718
Organism Escherichia coli O25b:H4-ST131 strain EC958

Toxin (Protein)


Gene name yjhX Uniprot ID B6I030
Locus tag EC958_RS25020 Protein ID WP_001054379.1
Coordinates 5006544..5006801 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag EC958_RS25015 Protein ID WP_000123957.1
Coordinates 5005981..5006532 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC958_RS24990 5001675..5002988 - 1314 WP_000460845.1 galactitol-specific PTS transporter subunit IIC -
EC958_RS24995 5003000..5003278 - 279 WP_000722973.1 PTS sugar transporter subunit IIB -
EC958_RS25000 5003275..5004396 - 1122 WP_000010833.1 M42 family metallopeptidase -
EC958_RS29725 5004641..5004757 - 117 Protein_4727 VOC family protein -
EC958_RS25005 5004795..5005055 - 261 WP_000077645.1 hypothetical protein -
EC958_RS25010 5005183..5005929 - 747 WP_000354249.1 class I SAM-dependent methyltransferase -
EC958_RS25015 5005981..5006532 - 552 WP_000123957.1 N-acetyltransferase Antitoxin
EC958_RS25020 5006544..5006801 - 258 WP_001054379.1 YjhX family toxin Toxin
EC958_RS28255 5007178..5007342 - 165 Protein_4732 GNAT family N-acetyltransferase -
EC958_RS25035 5008585..5009691 + 1107 Protein_4734 helicase YjhR -
EC958_RS25040 5010274..5011254 - 981 WP_000991462.1 9-O-acetyl-N-acetylneuraminic acid deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(19-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T285211 WP_001054379.1 NZ_HG941718:c5006801-5006544 [Escherichia coli O25b:H4-ST131]
MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20358.34 Da        Isoelectric Point: 6.4182

>AT285211 WP_000123957.1 NZ_HG941718:c5006532-5005981 [Escherichia coli O25b:H4-ST131]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
QPMNVTGHIQCAQALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B6I030

Antitoxin

Source ID Structure

References