Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1976274..1976542 Replicon chromosome
Accession NZ_HG941718
Organism Escherichia coli O25b:H4-ST131 strain EC958

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1976312..1976414 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1976274..1976542 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC958_RS10070 1973432..1974871 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EC958_RS10075 1974988..1975224 + 237 WP_001295499.1 DUF1480 family protein -
EC958_RS10080 1975329..1975520 + 192 WP_001296140.1 YebW family protein -
EC958_RS10085 1975521..1976177 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 1976274..1976542 + 269 - - Antitoxin
- 1976312..1976414 - 103 - - Toxin
EC958_RS10095 1976572..1976913 - 342 WP_000976472.1 YebY family protein -
EC958_RS10100 1976926..1977798 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
EC958_RS10105 1977802..1978176 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EC958_RS10110 1978315..1978545 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EC958_RS10115 1978647..1979303 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
EC958_RS10120 1979327..1979989 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T285194 NZ_HG941718:c1976414-1976312 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT285194 NZ_HG941718:1976274-1976542 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References