Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 797945..798565 Replicon chromosome
Accession NZ_HG938371
Organism Burkholderia cenocepacia H111

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I35_RS20105 Protein ID WP_006496016.1
Coordinates 798248..798565 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I35_RS20100 Protein ID WP_006496017.1
Coordinates 797945..798244 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I35_RS20075 793165..794436 + 1272 WP_006496020.1 Rieske 2Fe-2S domain-containing protein -
I35_RS20080 794452..794928 + 477 WP_006490977.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
I35_RS20085 794964..795290 + 327 WP_006496019.1 non-heme iron oxygenase ferredoxin subunit -
I35_RS20090 795280..796500 + 1221 WP_006496018.1 FAD-dependent oxidoreductase -
I35_RS20095 796610..797896 + 1287 WP_006490986.1 DUF445 domain-containing protein -
I35_RS20100 797945..798244 - 300 WP_006496017.1 putative addiction module antidote protein Antitoxin
I35_RS20105 798248..798565 - 318 WP_006496016.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I35_RS20110 798954..800594 + 1641 WP_006490980.1 acetolactate synthase large subunit -
I35_RS20115 800623..802056 + 1434 WP_006490987.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-102)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11817.59 Da        Isoelectric Point: 9.5691

>T285178 WP_006496016.1 NZ_HG938371:c798565-798248 [Burkholderia cenocepacia H111]
MPYSPPAFSIRTTDVFDAWFAGLPDRLAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRGTIWVILL
CGGDKSTQQADIRAAHAMLAHLDME

Download         Length: 318 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10636.10 Da        Isoelectric Point: 6.4771

>AT285178 WP_006496017.1 NZ_HG938371:c798244-797945 [Burkholderia cenocepacia H111]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAAV

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References