Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1755243..1755777 Replicon chromosome
Accession NZ_HG938370
Organism Burkholderia cenocepacia H111

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag I35_RS08090 Protein ID WP_021033200.1
Coordinates 1755478..1755777 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag I35_RS08085 Protein ID WP_021033199.1
Coordinates 1755243..1755488 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I35_RS08070 1751952..1752791 + 840 WP_006496453.1 Pyoverdine synthetase PvdF, N5-hydroxyornithine formyltransferase -
I35_RS08075 1752791..1753807 + 1017 WP_006496452.1 acetyltransferase -
I35_RS08080 1753965..1755128 + 1164 WP_006496451.1 amidohydrolase -
I35_RS08085 1755243..1755488 + 246 WP_021033199.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
I35_RS08090 1755478..1755777 + 300 WP_021033200.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I35_RS08095 1755868..1757172 - 1305 WP_006496450.1 cobyrinate a,c-diamide synthase -
I35_RS08100 1757175..1757777 - 603 WP_006476035.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
I35_RS08105 1757813..1758190 - 378 WP_006496449.1 cobalamin biosynthesis protein -
I35_RS08110 1758187..1758936 - 750 WP_006496448.1 uroporphyrinogen-III C-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11720.37 Da        Isoelectric Point: 6.9677

>T285177 WP_021033200.1 NZ_HG938370:1755478-1755777 [Burkholderia cenocepacia H111]
MAVKGRQLRLTPLAECDLEDIWRYTAEHWSPEQAEHYYRDLIGTMEALARGKKAGRICVVRDGYFRYPAGSHVVFYRETD
ETIDVIRVLHQRMDIERHL

Download         Length: 300 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8708.68 Da        Isoelectric Point: 7.3196

>AT285177 WP_021033199.1 NZ_HG938370:1755243-1755488 [Burkholderia cenocepacia H111]
MSRNTSVSLGDHFAEFVDAQVRSGRYGSASDVVRAGLRLLESHETQMRALQEALKAGEGSGTPKPFDSEAFLARMRATHG
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References