Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
| Location | 4391334..4391955 | Replicon | chromosome |
| Accession | NZ_HG938355 | ||
| Organism | Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 | ||
Toxin (Protein)
| Gene name | shpA | Uniprot ID | - |
| Locus tag | RG1141_RS21295 | Protein ID | WP_038548060.1 |
| Coordinates | 4391334..4391642 (+) | Length | 103 a.a. |
Antitoxin (Protein)
| Gene name | shpB | Uniprot ID | A0A068TEP8 |
| Locus tag | RG1141_RS21300 | Protein ID | WP_038548062.1 |
| Coordinates | 4391626..4391955 (+) | Length | 110 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG1141_RS21265 | 4386967..4387848 | - | 882 | WP_038548048.1 | alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ | - |
| RG1141_RS21270 | 4387897..4388112 | + | 216 | WP_038548050.1 | hypothetical protein | - |
| RG1141_RS21275 | 4388148..4389266 | - | 1119 | WP_038548052.1 | carbon-phosphorus lyase complex subunit PhnI | - |
| RG1141_RS21280 | 4389384..4389986 | - | 603 | WP_038548054.1 | phosphonate C-P lyase system protein PhnH | - |
| RG1141_RS21285 | 4389986..4390459 | - | 474 | WP_038548056.1 | phosphonate C-P lyase system protein PhnG | - |
| RG1141_RS21290 | 4390544..4391284 | + | 741 | WP_038548058.1 | phosphonate metabolism transcriptional regulator PhnF | - |
| RG1141_RS21295 | 4391334..4391642 | + | 309 | WP_038548060.1 | BrnT family toxin | Toxin |
| RG1141_RS21300 | 4391626..4391955 | + | 330 | WP_038548062.1 | BrnA antitoxin family protein | Antitoxin |
| RG1141_RS21305 | 4391971..4392606 | - | 636 | WP_038548065.1 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | - |
| RG1141_RS21310 | 4392632..4393450 | - | 819 | WP_038548068.1 | 4-hydroxy-tetrahydrodipicolinate reductase | - |
| RG1141_RS21315 | 4393606..4394628 | - | 1023 | WP_038548072.1 | glucokinase | - |
| RG1141_RS21320 | 4394637..4395017 | - | 381 | WP_038548075.1 | methylglyoxal synthase | - |
| RG1141_RS21325 | 4395137..4396195 | - | 1059 | WP_038548078.1 | penicillin-insensitive murein endopeptidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11808.24 Da Isoelectric Point: 4.6655
>T285167 WP_038548060.1 NZ_HG938355:4391334-4391642 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MNLMRFEWDRAKAATNVKKHGISFETAARVFADPFVLIEQDRIEGGEQRWQALGSVDGLAILLVAHTVYEDEEDDGQAYE
VIRIISARKADPRERRRYEEEL
MNLMRFEWDRAKAATNVKKHGISFETAARVFADPFVLIEQDRIEGGEQRWQALGSVDGLAILLVAHTVYEDEEDDGQAYE
VIRIISARKADPRERRRYEEEL
Download Length: 309 bp
Antitoxin
Download Length: 110 a.a. Molecular weight: 12534.28 Da Isoelectric Point: 9.9929
>AT285167 WP_038548062.1 NZ_HG938355:4391626-4391955 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MKKSSEIVRYEVDRDSLPPLTEKQRAELAALSKLPDEQIDYSDIPGLTDEQLQNAGRGRFYRPLKQQITARVDADVVDWL
KSQGKGYQARMNAILRREMLASLKSQKRN
MKKSSEIVRYEVDRDSLPPLTEKQRAELAALSKLPDEQIDYSDIPGLTDEQLQNAGRGRFYRPLKQQITARVDADVVDWL
KSQGKGYQARMNAILRREMLASLKSQKRN
Download Length: 330 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|