285163

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2491378..2491916 Replicon chromosome
Accession NZ_HG938355
Organism Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141

Toxin (Protein)


Gene name relE Uniprot ID A0A068T9Y4
Locus tag RG1141_RS12525 Protein ID WP_038544248.1
Coordinates 2491638..2491916 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A068T8Y4
Locus tag RG1141_RS12520 Protein ID WP_038544246.1
Coordinates 2491378..2491638 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG1141_RS12505 2487447..2488025 - 579 WP_038544239.1 ubiquinol-cytochrome c reductase iron-sulfur subunit -
RG1141_RS32045 2488417..2489355 + 939 WP_038544243.1 endonuclease/exonuclease/phosphatase family protein -
RG1141_RS12515 2489361..2491223 - 1863 WP_038544244.1 ABC transporter ATP-binding protein/permease -
RG1141_RS12520 2491378..2491638 + 261 WP_038544246.1 ribbon-helix-helix domain-containing protein Antitoxin
RG1141_RS12525 2491638..2491916 + 279 WP_038544248.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RG1141_RS12530 2491976..2493832 - 1857 WP_038544249.1 ABC transporter ATP-binding protein/permease -
RG1141_RS12535 2494220..2494705 + 486 WP_038544251.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
RG1141_RS12540 2494769..2495251 + 483 WP_162182336.1 redox-sensitive transcriptional activator SoxR -
RG1141_RS12545 2495327..2495629 + 303 WP_038544253.1 putative addiction module antidote protein -
RG1141_RS12550 2495788..2496216 + 429 WP_038544255.1 hypothetical protein -
RG1141_RS12555 2496226..2496483 - 258 WP_037076370.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-42)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10734.44 Da        Isoelectric Point: 10.2108

>T285163 WP_038544248.1 NZ_HG938355:2491638-2491916 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MELKWSSKAVSDLNRLHDFLAAVNAPAAARTAQNLAAAPKKLIQHPRLGERLDEFAPREIRRLLIGDYELRYEIQGEMIF
LLRIWHTRENRI

Download         Length: 279 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9836.22 Da        Isoelectric Point: 4.5702

>AT285163 WP_038544246.1 NZ_HG938355:2491378-2491638 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
METRVLTTHVPVQLAEKVDELATRLERSRGWIVKQALASWIELEEERRRLTLEAMADVDAGNVVDQEEVEKWVSSLGTDK
PLPRPL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068T9Y4

Antitoxin

Source ID Structure
AlphaFold DB A0A068T8Y4

References