Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 1403714..1404233 Replicon chromosome
Accession NZ_HG938355
Organism Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141

Toxin (Protein)


Gene name stbE Uniprot ID A0A068T6Y2
Locus tag RG1141_RS07230 Protein ID WP_038542473.1
Coordinates 1403952..1404233 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A068T5N6
Locus tag RG1141_RS07225 Protein ID WP_038542472.1
Coordinates 1403714..1403962 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG1141_RS07205 1399502..1401313 + 1812 WP_038549108.1 ABC transporter ATP-binding protein -
RG1141_RS07210 1401450..1401902 + 453 WP_051899695.1 hypothetical protein -
RG1141_RS07215 1401895..1402698 - 804 WP_038542467.1 DNA repair protein RadC -
RG1141_RS07220 1402702..1403538 - 837 WP_038542469.1 type I methionyl aminopeptidase -
RG1141_RS07225 1403714..1403962 + 249 WP_038542472.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
RG1141_RS07230 1403952..1404233 + 282 WP_038542473.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RG1141_RS07235 1404209..1404937 - 729 WP_038542475.1 DNA/RNA nuclease SfsA -
RG1141_RS07240 1404949..1406808 - 1860 WP_038542478.1 class I poly(R)-hydroxyalkanoic acid synthase -
RG1141_RS07245 1406932..1407333 + 402 WP_038542480.1 hypothetical protein -
RG1141_RS07250 1407496..1408713 + 1218 WP_038542482.1 LL-diaminopimelate aminotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10902.77 Da        Isoelectric Point: 10.7257

>T285162 WP_038542473.1 NZ_HG938355:1403952-1404233 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MSCELAFLDVALKEWRKLDSNIREQFKKKLAERLENPRVAAAQLHGSKNRYKIKLRSIGYRLVYEVRDTQLIVLVVAVGR
RDRDAVYKAAEKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8737.05 Da        Isoelectric Point: 4.1225

>AT285162 WP_038542472.1 NZ_HG938355:1403714-1403962 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MVSIVLAEVTASVSELKRNPMGTVAAGDGAPVAILNRNEPAFYCVPAKAYEAMMDRLEDLELNALADSRAGETVIKVTLD
EL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068T6Y2

Antitoxin

Source ID Structure
AlphaFold DB A0A068T5N6

References