285160

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 863131..863726 Replicon chromosome
Accession NZ_HG938355
Organism Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141

Toxin (Protein)


Gene name vapC Uniprot ID A0A068T7C2
Locus tag RG1141_RS04475 Protein ID WP_038541376.1
Coordinates 863131..863496 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A068SLL3
Locus tag RG1141_RS04480 Protein ID WP_038541378.1
Coordinates 863493..863726 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG1141_RS04450 858175..859401 - 1227 WP_051899673.1 efflux RND transporter periplasmic adaptor subunit -
RG1141_RS04455 859603..859806 - 204 WP_038541367.1 hypothetical protein -
RG1141_RS04460 859907..860275 - 369 WP_038541369.1 hypothetical protein -
RG1141_RS04465 860401..861204 - 804 WP_038541371.1 SDR family oxidoreductase -
RG1141_RS04470 861463..863124 + 1662 WP_038541374.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
RG1141_RS04475 863131..863496 - 366 WP_038541376.1 PIN domain-containing protein Toxin
RG1141_RS04480 863493..863726 - 234 WP_038541378.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
RG1141_RS04485 863919..864530 + 612 WP_038541380.1 L,D-transpeptidase -
RG1141_RS04490 864606..865622 - 1017 WP_038541382.1 zinc-binding alcohol dehydrogenase family protein -
RG1141_RS04495 865746..866141 + 396 WP_038541384.1 helix-turn-helix transcriptional regulator -
RG1141_RS04500 866336..867577 - 1242 WP_038541386.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-112)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13539.92 Da        Isoelectric Point: 7.4683

>T285160 WP_038541376.1 NZ_HG938355:c863496-863131 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
VILLDTSIWIDHLRKREEAVEFLLKRKQVLVHPFVIGEVALGPMPRYDLVLQSLSELPQALVASDPEVLLLIRQHSLMGS
GIGYVDAHLLASTRLHEGTRLLTRDKRLARIATALGIGYEP

Download         Length: 366 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8643.83 Da        Isoelectric Point: 6.3355

>AT285160 WP_038541378.1 NZ_HG938355:c863726-863493 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MRTTVTIDDKLLARAQEVTGIKERSLLLKEALTRLIQEEAARRLIALGGSAPDLEAPPRRRWNLDGTWGGSDWDKSE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068T7C2

Antitoxin

Source ID Structure
AlphaFold DB A0A068SLL3

References