Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 735148..735728 | Replicon | chromosome |
Accession | NZ_HG938355 | ||
Organism | Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | RG1141_RS03780 | Protein ID | WP_038541017.1 |
Coordinates | 735148..735402 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | A0A068T6Z6 |
Locus tag | RG1141_RS03785 | Protein ID | WP_038541020.1 |
Coordinates | 735399..735728 (+) | Length | 110 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RG1141_RS03750 | 730439..731281 | + | 843 | WP_038540999.1 | metallophosphoesterase | - |
RG1141_RS03755 | 731284..731928 | - | 645 | WP_038541003.1 | ThuA domain-containing protein | - |
RG1141_RS03760 | 732025..732714 | - | 690 | WP_038541006.1 | YafY family transcriptional regulator | - |
RG1141_RS03765 | 732850..733482 | + | 633 | WP_038541008.1 | LysE family translocator | - |
RG1141_RS03770 | 733664..734104 | + | 441 | WP_038541011.1 | cytochrome c | - |
RG1141_RS03775 | 734189..735103 | + | 915 | WP_157885084.1 | cytochrome c | - |
RG1141_RS03780 | 735148..735402 | + | 255 | WP_038541017.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
RG1141_RS03785 | 735399..735728 | + | 330 | WP_038541020.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
RG1141_RS03790 | 735745..736242 | - | 498 | WP_038541023.1 | GNAT family N-acetyltransferase | - |
RG1141_RS03795 | 736420..737394 | - | 975 | WP_038548903.1 | prolyl aminopeptidase | - |
RG1141_RS03800 | 737527..737820 | + | 294 | WP_038541026.1 | hypothetical protein | - |
RG1141_RS03805 | 737807..738169 | + | 363 | WP_038541029.1 | hypothetical protein | - |
RG1141_RS03810 | 738189..738602 | - | 414 | WP_038541031.1 | helix-turn-helix domain-containing protein | - |
RG1141_RS03815 | 738756..739316 | - | 561 | WP_038541034.1 | hypothetical protein | - |
RG1141_RS03820 | 739444..739716 | + | 273 | WP_038541037.1 | Ni(II)/Co(II)-sensing transcriptional repressor DmeR | - |
RG1141_RS03825 | 739737..740720 | + | 984 | WP_038541041.1 | CDF family Co(II)/Ni(II) efflux transporter DmeF | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9576.02 Da Isoelectric Point: 8.0701
>T285158 WP_038541017.1 NZ_HG938355:735148-735402 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MNSKQRKTLVAIFQDPVSPSIDWSDVENLLIAVGCHLLEGSGSRVRFEKDGLVVFFHRPHPDKEAKRYQIKDARLFLSQL
GIEP
MNSKQRKTLVAIFQDPVSPSIDWSDVENLLIAVGCHLLEGSGSRVRFEKDGLVVFFHRPHPDKEAKRYQIKDARLFLSQL
GIEP
Download Length: 255 bp
Antitoxin
Download Length: 110 a.a. Molecular weight: 11919.40 Da Isoelectric Point: 4.9230
>AT285158 WP_038541020.1 NZ_HG938355:735399-735728 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MNVLEYKGYSARIEFDAEDEIFVGHIAGIADVVGFHADSVVDLKTAFHEAVDDYLETCERLGRSPHKPYSGRVMFRIDPD
VHARAAKAAELAGKSLNEWAGEILAKAAG
MNVLEYKGYSARIEFDAEDEIFVGHIAGIADVVGFHADSVVDLKTAFHEAVDDYLETCERLGRSPHKPYSGRVMFRIDPD
VHARAAKAAELAGKSLNEWAGEILAKAAG
Download Length: 330 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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