285157

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 670242..670844 Replicon chromosome
Accession NZ_HG938355
Organism Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RG1141_RS03380 Protein ID WP_038548874.1
Coordinates 670242..670487 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A068T6T1
Locus tag RG1141_RS03385 Protein ID WP_038540814.1
Coordinates 670491..670844 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG1141_RS03360 666470..667828 + 1359 WP_038540805.1 virulence factor family protein -
RG1141_RS31250 667955..668170 + 216 WP_080719124.1 ribbon-helix-helix protein, CopG family -
RG1141_RS03370 668164..668540 + 377 Protein_673 type II toxin-antitoxin system VapC family toxin -
RG1141_RS03375 668541..670190 - 1650 WP_038540811.1 choline dehydrogenase -
RG1141_RS03380 670242..670487 + 246 WP_038548874.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
RG1141_RS03385 670491..670844 + 354 WP_038540814.1 helix-turn-helix transcriptional regulator Antitoxin
RG1141_RS03390 670853..672316 - 1464 WP_038540817.1 betaine-aldehyde dehydrogenase -
RG1141_RS03395 672318..673841 - 1524 WP_038540820.1 choline-sulfatase -
RG1141_RS03405 674374..674921 + 548 Protein_679 HdeD family acid-resistance protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(58-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9049.61 Da        Isoelectric Point: 10.9252

>T285157 WP_038548874.1 NZ_HG938355:670242-670487 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MKAVLYSKVAQKSLSRMQPKRQAAIRAKVDAFARGDRVDLKRLEGSALVRIRVGNDRIIIDEETNLVVVIDVGPRGGIYK
E

Download         Length: 246 bp

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13115.97 Da        Isoelectric Point: 4.1723

>AT285157 WP_038540814.1 NZ_HG938355:670491-670844 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MGVFDKTVIDGKSYVLVPEDDFEDMMDTIKANEILARIAAGEETWPAELVYELLETESRIRTFRNYRKMTVSELAEAAGI
SQPYLSEIETGKKTGSVDVLKRIAAVLKVDLDDLVLD

Download         Length: 354 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A068T6T1

References