Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 658927..659461 Replicon chromosome
Accession NZ_HG938355
Organism Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141

Toxin (Protein)


Gene name parE Uniprot ID A0A068T4K5
Locus tag RG1141_RS03325 Protein ID WP_038540785.1
Coordinates 659162..659461 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A068T3J2
Locus tag RG1141_RS03320 Protein ID WP_038540781.1
Coordinates 658927..659172 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG1141_RS03300 654784..656283 - 1500 WP_038540768.1 sulfate adenylyltransferase subunit CysN -
RG1141_RS03305 656285..657238 - 954 WP_038540771.1 sulfate adenylyltransferase subunit CysD -
RG1141_RS03310 657280..658050 - 771 WP_038540775.1 phosphoadenylyl-sulfate reductase -
RG1141_RS03315 658411..658866 + 456 WP_038540778.1 Rrf2 family transcriptional regulator -
RG1141_RS03320 658927..659172 + 246 WP_038540781.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
RG1141_RS03325 659162..659461 + 300 WP_038540785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RG1141_RS03330 659746..660747 + 1002 WP_173426768.1 sulfate ABC transporter substrate-binding protein -
RG1141_RS03335 660761..661618 + 858 WP_038540790.1 sulfate ABC transporter permease subunit CysT -
RG1141_RS03340 661611..662489 + 879 WP_038540793.1 sulfate ABC transporter permease subunit CysW -
RG1141_RS03345 662505..663542 + 1038 WP_038540795.1 sulfate/molybdate ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11535.05 Da        Isoelectric Point: 6.0798

>T285156 WP_038540785.1 NZ_HG938355:659162-659461 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MAAKGRDYKLSPLAEEDLEDIWGYTVETWSWEQAERYHDELISTLEGLAAGRKLGRPVDIRQGYFKYSVGAHCVFYRFSE
SAIDIIRILHQKMDVSRHL

Download         Length: 300 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8937.99 Da        Isoelectric Point: 7.3199

>AT285156 WP_038540781.1 NZ_HG938355:658927-659172 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MARNTSISLGDHFASFIDTQVESGRYGSASDVVRAGLRLLEEHEARVKALQDALIAGEESGPPQPFDNQAFLKRMRARHG
R

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068T4K5

Antitoxin

Source ID Structure
AlphaFold DB A0A068T3J2

References