285155

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 583949..584508 Replicon chromosome
Accession NZ_HG938355
Organism Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag RG1141_RS02895 Protein ID WP_038540580.1
Coordinates 584260..584508 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID A0A068T6L4
Locus tag RG1141_RS02890 Protein ID WP_038540576.1
Coordinates 583949..584263 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG1141_RS02870 579421..580647 + 1227 WP_038548828.1 AGE family epimerase/isomerase -
RG1141_RS02875 580652..581719 + 1068 WP_038540567.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
RG1141_RS02880 581741..582916 + 1176 WP_038540570.1 mannonate dehydratase -
RG1141_RS02885 582941..583942 + 1002 WP_038540574.1 Gfo/Idh/MocA family oxidoreductase -
RG1141_RS02890 583949..584263 - 315 WP_038540576.1 BrnA antitoxin family protein Antitoxin
RG1141_RS02895 584260..584508 - 249 WP_038540580.1 BrnT family toxin Toxin
RG1141_RS02900 584598..585698 - 1101 WP_038540584.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
RG1141_RS02905 585711..586823 - 1113 WP_038540587.1 chorismate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(26-102)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9286.87 Da        Isoelectric Point: 10.2014

>T285155 WP_038540580.1 NZ_HG938355:c584508-584260 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MKIIWDETKRIVNLEKHGLDFADLYFEFFATAVTTPARKARSKAVGRLKDGTIVVIFLTLGSEAISVISMRPARKDERSM
VE

Download         Length: 249 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11829.68 Da        Isoelectric Point: 9.8648

>AT285155 WP_038540576.1 NZ_HG938355:c584263-583949 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
MNIKHEKQKEFRPGRGYTKEDWDAVDSPPLTAEEMASMRPFREVFPEMAAKMEQAIAARGRPKVEAPKVAVTLRLDPDVL
EKYKASGKDWRAKMAEELRKAAGL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A068T6L4

References