285153

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 1558278..1558825 Replicon plasmid pHAMBI540a
Accession NZ_HG938354
Organism Neorhizobium galegae bv. orientalis str. HAMBI 540

Toxin (Protein)


Gene name parE Uniprot ID A0A068T425
Locus tag RG540_RS29905 Protein ID WP_041365974.1
Coordinates 1558278..1558571 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A068T289
Locus tag RG540_RS29910 Protein ID WP_041365976.1
Coordinates 1558571..1558825 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG540_RS29885 1554341..1555429 + 1089 WP_041365967.1 DNA polymerase IV -
RG540_RS29890 1555735..1556043 + 309 WP_041365969.1 hypothetical protein -
RG540_RS32710 1556915..1557300 - 386 Protein_1496 BA14K family protein -
RG540_RS29900 1557248..1557451 + 204 WP_040125337.1 cold-shock protein -
RG540_RS29905 1558278..1558571 - 294 WP_041365974.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RG540_RS29910 1558571..1558825 - 255 WP_041365976.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
RG540_RS29915 1559144..1561111 - 1968 WP_041365978.1 Fe(3+)-hydroxamate ABC transporter permease FhuB -
RG540_RS29920 1561108..1561992 - 885 WP_041365980.1 iron-siderophore ABC transporter substrate-binding protein -
RG540_RS29925 1562006..1562818 - 813 WP_041365982.1 ATP-binding cassette domain-containing protein -
RG540_RS29930 1562870..1563742 - 873 WP_041366601.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - ddhA / htpB 1..1807065 1807065


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-61)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11224.80 Da        Isoelectric Point: 5.5922

>T285153 WP_041365974.1 NZ_HG938354:c1558571-1558278 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MRFSFSVEAEEDIIAIAEQSVRMFGSAQARRYYDELFAVLDLIAANPRMAREREEISPPVRIHPFKAHLVVYRIEENGAI
FVIRIRHGHEDWAGDPV

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9293.46 Da        Isoelectric Point: 10.1451

>AT285153 WP_041365976.1 NZ_HG938354:c1558825-1558571 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MATMNVSLPDPMKDWVEAQARTGRYSNASDYVRDLIRRDQARSDKIAAMQRFVDDGLKSGVGGRSKDELFAAAVVRAETT
RGSK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068T425

Antitoxin

Source ID Structure
AlphaFold DB A0A068T289

References