Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 1481116..1481635 Replicon chromosome
Accession NZ_HG938353
Organism Neorhizobium galegae bv. orientalis str. HAMBI 540

Toxin (Protein)


Gene name stbE Uniprot ID A0A068SPD5
Locus tag RG540_RS07575 Protein ID WP_038586268.1
Coordinates 1481354..1481635 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A068SN99
Locus tag RG540_RS07570 Protein ID WP_038586265.1
Coordinates 1481116..1481364 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG540_RS07550 1476581..1477345 + 765 WP_038586255.1 DUF1028 domain-containing protein -
RG540_RS07555 1477372..1479183 + 1812 WP_038593297.1 ABC transporter ATP-binding protein -
RG540_RS07560 1479297..1480100 - 804 WP_038586259.1 DNA repair protein RadC -
RG540_RS07565 1480104..1480940 - 837 WP_038586262.1 type I methionyl aminopeptidase -
RG540_RS07570 1481116..1481364 + 249 WP_038586265.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
RG540_RS07575 1481354..1481635 + 282 WP_038586268.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RG540_RS07580 1481611..1482339 - 729 WP_038586271.1 DNA/RNA nuclease SfsA -
RG540_RS07585 1482351..1484210 - 1860 WP_038586274.1 class I poly(R)-hydroxyalkanoic acid synthase -
RG540_RS07590 1484334..1484735 + 402 WP_038586276.1 hypothetical protein -
RG540_RS07595 1484898..1486115 + 1218 WP_038586280.1 LL-diaminopimelate aminotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11022.85 Da        Isoelectric Point: 10.4957

>T285145 WP_038586268.1 NZ_HG938353:1481354-1481635 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MSYELAFLDVALKEWRKLDSNIREQFKKKLAERLEDPRVTAAQLHVSKDRYKIKLRSIGYRLVYEVRDTQLIVLVVAVGR
RDRDAVYKGAEKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8771.06 Da        Isoelectric Point: 4.1225

>AT285145 WP_038586265.1 NZ_HG938353:1481116-1481364 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MVSIVLAEVTASVSELKRNPMGTVAAGDGAPVAILNRNEPAFYCVPAKAYEAMMDRLEDFELNALADSRAGETVIKVTLD
EL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068SPD5

Antitoxin

Source ID Structure
AlphaFold DB A0A068SN99

References