285140

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 572254..572813 Replicon chromosome
Accession NZ_HG938353
Organism Neorhizobium galegae bv. orientalis str. HAMBI 540

Toxin (Protein)


Gene name brnT Uniprot ID A0A068SLX1
Locus tag RG540_RS02700 Protein ID WP_038584250.1
Coordinates 572565..572813 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID A0A068SNQ2
Locus tag RG540_RS02695 Protein ID WP_038584248.1
Coordinates 572254..572568 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG540_RS02675 567724..568950 + 1227 WP_038584242.1 AGE family epimerase/isomerase -
RG540_RS02680 568955..570022 + 1068 WP_038584244.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
RG540_RS02685 570044..571219 + 1176 WP_038584245.1 mannonate dehydratase -
RG540_RS02690 571246..572247 + 1002 WP_038584247.1 Gfo/Idh/MocA family oxidoreductase -
RG540_RS02695 572254..572568 - 315 WP_038584248.1 BrnA antitoxin family protein Antitoxin
RG540_RS02700 572565..572813 - 249 WP_038584250.1 BrnT family toxin Toxin
RG540_RS02705 572903..574003 - 1101 WP_038584252.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
RG540_RS02710 574016..575113 - 1098 WP_038584254.1 chorismate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(26-102)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9270.91 Da        Isoelectric Point: 10.1451

>T285140 WP_038584250.1 NZ_HG938353:c572813-572565 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MKIIWDETKRIVNLEKHGLDFADLYFEFFATAVTTPAKKARSKAVGRLKDGTIVVIFLVLGSEAISVISMRPARKDERSM
IE

Download         Length: 249 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11827.70 Da        Isoelectric Point: 9.9713

>AT285140 WP_038584248.1 NZ_HG938353:c572568-572254 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MNIKHEKQKEFRPGRGYTKEDWDAVDSPPLTAEEMASMRPFREVFPEMAAKMEQAIAARGRPKLEAPKVAVTLRLDPDVL
EKFKASGKDWRAKMAEELRKAAGL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068SLX1

Antitoxin

Source ID Structure
AlphaFold DB A0A068SNQ2

References