Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3556515..3556984 Replicon chromosome
Accession NZ_HG916826
Organism Pseudomonas pseudoalcaligenes CECT 5344 strain CECT5344

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BN5_RS22855 Protein ID WP_003459396.1
Coordinates 3556515..3556790 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W6R134
Locus tag BN5_RS16685 Protein ID WP_003459395.1
Coordinates 3556790..3556984 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN5_RS16670 3554969..3555385 + 417 WP_003459398.1 type IV pilin protein -
BN5_RS16675 3555519..3556463 - 945 WP_003459397.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
BN5_RS22855 3556515..3556790 - 276 WP_003459396.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
BN5_RS16685 3556790..3556984 - 195 WP_003459395.1 hypothetical protein Antitoxin
BN5_RS16690 3557014..3557460 - 447 WP_003459394.1 peptidylprolyl isomerase -
BN5_RS16695 3557457..3557966 - 510 WP_003459393.1 signal peptidase II -
BN5_RS16700 3557959..3560790 - 2832 WP_003459392.1 isoleucine--tRNA ligase -
BN5_RS16705 3560787..3561755 - 969 WP_003459391.1 bifunctional riboflavin kinase/FAD synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - pilS / pilR / algW 3520707..3706356 185649


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10419.02 Da        Isoelectric Point: 6.7154

>T285133 WP_003459396.1 NZ_HG916826:c3556790-3556515 [Pseudomonas pseudoalcaligenes CECT 5344]
MLPIIWRDSARADLAEIIRYIADEALQAARQLKNYLESAVLPLAEHPYLYRSGRVPGTRELVAHPNYVLVYRVAAECIEV
VSVLHSRQEYP

Download         Length: 276 bp

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7366.20 Da        Isoelectric Point: 5.0495

>AT285133 WP_003459395.1 NZ_HG916826:c3556984-3556790 [Pseudomonas pseudoalcaligenes CECT 5344]
MSVQLSPIVSEFETQEQADSHDRWFRRKVKESLDDSRPGVPHDQVMAEMEAIIVQAEARQRGRG

Download         Length: 195 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W6R134

References