Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 688401..688942 Replicon chromosome
Accession NZ_HG916826
Organism Pseudomonas pseudoalcaligenes CECT 5344 strain CECT5344

Toxin (Protein)


Gene name relE Uniprot ID W6QQQ0
Locus tag BN5_RS03090 Protein ID WP_039965077.1
Coordinates 688401..688697 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W6QYQ7
Locus tag BN5_RS03095 Protein ID WP_004425059.1
Coordinates 688685..688942 (-) Length 86 a.a.

Genomic Context


BN5_RS03065BN5_RS03070BN5_RS03075BN5_RS22185BN5_RS03085BN5_RS03105BN5_RS03115BN5_RS03120BN5_RS03090BN5_RS03095BN5_RS03100BN5_RS03110BN5_RS03125
Location: 683461..684900 (1440 bp)
Type: Others
Protein ID: WP_004425078.1
Location: 684903..685910 (1008 bp)
Type: Others
Protein ID: WP_004425076.1
Location: 686107..686253 (147 bp)
Type: Others
Protein ID: WP_004425073.1
Location: 686324..687078 (755 bp)
Type: Others
Protein ID: Protein_619
Location: 687078..688397 (1320 bp)
Type: Others
Protein ID: WP_004425062.1
Location: 690379..691155 (777 bp)
Type: Others
Protein ID: WP_004425053.1
Location: 692422..692670 (249 bp)
Type: Others
Protein ID: WP_004425048.1
Location: 692739..693017 (279 bp)
Type: Others
Protein ID: WP_004425044.1
Location: 688401..688697 (297 bp)
Type: Toxin
Protein ID: WP_039965077.1
Location: 688685..688942 (258 bp)
Type: Antitoxin
Protein ID: WP_004425059.1
Location: 689011..690135 (1125 bp)
Type: Others
Protein ID: WP_004425056.1
Location: 691156..692181 (1026 bp)
Type: Others
Protein ID: WP_004425051.1
Location: 693279..693755 (477 bp)
Type: Others
Protein ID: WP_039965075.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BN5_RS03065683461..684900+1440WP_004425078.1cytochrome ubiquinol oxidase subunit I-
BN5_RS03070684903..685910+1008WP_004425076.1cytochrome d ubiquinol oxidase subunit II-
BN5_RS03075686107..686253+147WP_004425073.1DUF2474 domain-containing protein-
BN5_RS22185686324..687078+755Protein_619hypothetical protein-
BN5_RS03085687078..688397+1320WP_004425062.1Zn-dependent protease-
BN5_RS03090688401..688697-297WP_039965077.1type II toxin-antitoxin system RelE/ParE family toxinToxin
BN5_RS03095688685..688942-258WP_004425059.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
BN5_RS03100689011..690135-1125WP_004425056.1class I SAM-dependent methyltransferase-
BN5_RS03105690379..691155+777WP_004425053.1ferredoxin--NADP reductase-
BN5_RS03110691156..692181-1026WP_004425051.1hemolysin family protein-
BN5_RS03115692422..692670+249WP_004425048.1YdcH family protein-
BN5_RS03120692739..693017+279WP_004425044.1DUF465 domain-containing protein-
BN5_RS03125693279..693755-477WP_039965075.1GNAT family N-acetyltransferase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11393.23 Da        Isoelectric Point: 5.5623

>T285126 WP_039965077.1 NZ_HG916826:c688697-688401 [Pseudomonas pseudoalcaligenes CECT 5344]
MAEIVWTNTALEQLDDLAHYIALDKPDAARALVMRAVETVSRLADFPLSGRVPDELPHSVYREIVIPPCRIFYRYTDTTV
FIIHIMREERVLRAHMLE

Download         Length: 297 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9715.23 Da        Isoelectric Point: 7.3181

>AT285126 WP_004425059.1 NZ_HG916826:c688942-688685 [Pseudomonas pseudoalcaligenes CECT 5344]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALARGERAVIEGNTANHEQAKERL
SKWLK

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBW6QQQ0


Antitoxin

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Source
ID
Structure
AlphaFold DBW6QYQ7

References