Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES-Xre
Location 1595919..1596823 Replicon chromosome
Accession NZ_HG916765
Organism Castellaniella defragrans 65Phen

Toxin (Protein)


Gene name slvT Uniprot ID W8WWM8
Locus tag BN940_RS07240 Protein ID WP_043681607.1
Coordinates 1596287..1596823 (+) Length 179 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag BN940_RS07235 Protein ID WP_043681604.1
Coordinates 1595919..1596290 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN940_RS07215 1590966..1591880 + 915 WP_043681593.1 M14 family metallocarboxypeptidase -
BN940_RS07220 1591885..1592817 + 933 WP_043681596.1 glyoxylate/hydroxypyruvate reductase A -
BN940_RS07225 1592884..1593927 - 1044 WP_198408314.1 ADP-ribosylglycohydrolase family protein -
BN940_RS07230 1593927..1595462 - 1536 WP_043681601.1 sensor domain-containing diguanylate cyclase -
BN940_RS07235 1595919..1596290 + 372 WP_043681604.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
BN940_RS07240 1596287..1596823 + 537 WP_043681607.1 RES family NAD+ phosphorylase Toxin
BN940_RS07245 1596955..1597719 - 765 WP_043681610.1 hypothetical protein -
BN940_RS07250 1597735..1598061 - 327 WP_043681613.1 BON domain-containing protein -
BN940_RS07255 1598180..1598368 - 189 WP_043681615.1 DUF1778 domain-containing protein -
BN940_RS07265 1598825..1600345 + 1521 WP_052355675.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(16-161)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 19627.15 Da        Isoelectric Point: 4.5567

>T285121 WP_043681607.1 NZ_HG916765:1596287-1596823 [Castellaniella defragrans 65Phen]
MIPAITLGKAEEEAYYRVITPIYAGTPLSGAGAARQGGRFNRRGQEALYLSTDEATALAEYKQDNPWLPPGTICTFFVRE
LRVADFSAGFDPEMWPALWSDFSVDWRAEWFGKSIEPPTWYMADDVVAEGLDGILFPSQAHPGGTNLVVYRSSVRPVAQL
RVYDPGGALRKIAPPANE

Download         Length: 537 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13723.57 Da        Isoelectric Point: 6.4736

>AT285121 WP_043681604.1 NZ_HG916765:1595919-1596290 [Castellaniella defragrans 65Phen]
MSTVLQRPFAEQFREPDTPYLSPARIGEFFGFQVQELAERAHVHRNTPTARPQAPQLQKYLQDMVRVLTVATEMTGDEKR
AAFLLRNEPLRAFGYKTADTLIQEGRADAVIAYLESLAGGAAG

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W8WWM8

Antitoxin

Source ID Structure

References