Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 5928845..5929915 | Replicon | chromosome |
| Accession | NC_019682 | ||
| Organism | Calothrix sp. PCC 7507 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | CAL7507_RS25390 | Protein ID | WP_015131348.1 |
| Coordinates | 5928845..5929414 (-) | Length | 190 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | K9PR16 |
| Locus tag | CAL7507_RS25395 | Protein ID | WP_015131349.1 |
| Coordinates | 5929442..5929915 (-) | Length | 158 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CAL7507_RS25365 | 5924814..5925653 | + | 840 | WP_015131342.1 | fatty acid desaturase | - |
| CAL7507_RS25370 | 5925858..5926244 | - | 387 | WP_015131343.1 | type II toxin-antitoxin system VapC family toxin | - |
| CAL7507_RS25375 | 5926241..5926435 | - | 195 | WP_015131344.1 | hypothetical protein | - |
| CAL7507_RS31965 | 5926506..5926706 | + | 201 | WP_015131345.1 | hypothetical protein | - |
| CAL7507_RS25380 | 5926660..5927580 | + | 921 | WP_015131346.1 | 3'-5' exonuclease | - |
| CAL7507_RS25385 | 5927979..5928821 | + | 843 | WP_015131347.1 | tetratricopeptide repeat protein | - |
| CAL7507_RS25390 | 5928845..5929414 | - | 570 | WP_015131348.1 | PIN domain-containing protein | Toxin |
| CAL7507_RS25395 | 5929442..5929915 | - | 474 | WP_015131349.1 | helix-turn-helix domain-containing protein | Antitoxin |
| CAL7507_RS25400 | 5930130..5930765 | - | 636 | WP_015131350.1 | uracil phosphoribosyltransferase | - |
| CAL7507_RS25405 | 5930835..5932064 | - | 1230 | WP_015131351.1 | URC4/urg3 family protein | - |
| CAL7507_RS25410 | 5932134..5933393 | - | 1260 | WP_015131352.1 | GTP cyclohydrolase II | - |
| CAL7507_RS25415 | 5933707..5934177 | + | 471 | WP_015131353.1 | tetratricopeptide repeat protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21446.73 Da Isoelectric Point: 6.2163
>T28506 WP_015131348.1 NC_019682:c5929414-5928845 [Calothrix sp. PCC 7507]
VSNFTAIYDACVLYPAPLRDFLMRLAVTDLFRARWTDAIHSEWIRNVLKDRPDLTLEKLTRTKNLMNSHVRDCLVTGYEA
LIVGLQLPDQNDLHVLAAAICCNASTIVTFNVKDFPAQALSPYGIESQHPDDFILHLIDLNPIEICKVVKRHRSSLKNPP
KTSEEYLESLLRQGLPQSVTALQDLCYDI
VSNFTAIYDACVLYPAPLRDFLMRLAVTDLFRARWTDAIHSEWIRNVLKDRPDLTLEKLTRTKNLMNSHVRDCLVTGYEA
LIVGLQLPDQNDLHVLAAAICCNASTIVTFNVKDFPAQALSPYGIESQHPDDFILHLIDLNPIEICKVVKRHRSSLKNPP
KTSEEYLESLLRQGLPQSVTALQDLCYDI
Download Length: 570 bp
>T28506 NC_019682:c5929414-5928845 [Calothrix sp. PCC 7507]
GTGTCTAATTTCACAGCTATTTATGATGCATGTGTCTTATATCCAGCACCATTGAGAGATTTTCTGATGCGGCTTGCAGT
CACCGACCTATTTAGGGCACGGTGGACGGACGCAATTCACTCAGAGTGGATTAGAAACGTTTTAAAGGATCGTCCTGATC
TCACGCTTGAGAAGCTTACCAGAACTAAAAATCTGATGAATAGCCATGTTCGGGATTGTCTAGTTACAGGTTATGAAGCA
CTTATCGTAGGTTTACAACTTCCAGATCAAAATGATCTCCATGTTCTTGCAGCAGCTATTTGTTGTAATGCAAGTACTAT
AGTCACTTTTAACGTTAAAGATTTTCCTGCTCAAGCTCTTTCTCCATACGGTATTGAGTCCCAGCATCCAGATGACTTCA
TTCTGCATCTGATTGACCTTAACCCAATAGAAATTTGCAAAGTTGTAAAGAGGCACAGAAGTAGTCTTAAGAATCCCCCT
AAGACATCTGAAGAGTACTTAGAATCGCTTCTAAGGCAGGGACTACCACAATCAGTTACTGCTCTACAAGATTTGTGCTA
TGACATTTAG
GTGTCTAATTTCACAGCTATTTATGATGCATGTGTCTTATATCCAGCACCATTGAGAGATTTTCTGATGCGGCTTGCAGT
CACCGACCTATTTAGGGCACGGTGGACGGACGCAATTCACTCAGAGTGGATTAGAAACGTTTTAAAGGATCGTCCTGATC
TCACGCTTGAGAAGCTTACCAGAACTAAAAATCTGATGAATAGCCATGTTCGGGATTGTCTAGTTACAGGTTATGAAGCA
CTTATCGTAGGTTTACAACTTCCAGATCAAAATGATCTCCATGTTCTTGCAGCAGCTATTTGTTGTAATGCAAGTACTAT
AGTCACTTTTAACGTTAAAGATTTTCCTGCTCAAGCTCTTTCTCCATACGGTATTGAGTCCCAGCATCCAGATGACTTCA
TTCTGCATCTGATTGACCTTAACCCAATAGAAATTTGCAAAGTTGTAAAGAGGCACAGAAGTAGTCTTAAGAATCCCCCT
AAGACATCTGAAGAGTACTTAGAATCGCTTCTAAGGCAGGGACTACCACAATCAGTTACTGCTCTACAAGATTTGTGCTA
TGACATTTAG
Antitoxin
Download Length: 158 a.a. Molecular weight: 17493.85 Da Isoelectric Point: 4.6382
>AT28506 WP_015131349.1 NC_019682:c5929915-5929442 [Calothrix sp. PCC 7507]
MTVNTYQASRIAVPTEEDATLAKKSSQTLASYVQDDDPCRTIKVVLDNATSETVTIPAAAFHLLVDILTQMAKGNAVTLI
PVHAELTTQEAADILNVSRPYLVGLLESGEMPYRKVGTRRRVRYQDLLNYKNQIDTFRMQALDELTAQAQELDMGYE
MTVNTYQASRIAVPTEEDATLAKKSSQTLASYVQDDDPCRTIKVVLDNATSETVTIPAAAFHLLVDILTQMAKGNAVTLI
PVHAELTTQEAADILNVSRPYLVGLLESGEMPYRKVGTRRRVRYQDLLNYKNQIDTFRMQALDELTAQAQELDMGYE
Download Length: 474 bp
>AT28506 NC_019682:c5929915-5929442 [Calothrix sp. PCC 7507]
ATGACAGTCAATACATACCAAGCTAGTAGGATTGCTGTACCTACAGAAGAGGATGCTACGCTAGCTAAAAAAAGTAGTCA
AACTTTGGCATCCTATGTACAGGATGATGATCCATGCCGTACTATTAAAGTTGTGCTAGATAACGCTACAAGTGAAACGG
TTACTATACCAGCAGCAGCTTTTCATCTGCTTGTTGACATCTTGACACAAATGGCTAAAGGTAATGCTGTTACTCTTATA
CCCGTACATGCAGAACTCACGACACAAGAAGCAGCTGATATTTTAAATGTTTCTCGTCCTTATTTGGTAGGGTTATTGGA
ATCTGGAGAGATGCCATACCGTAAAGTGGGAACACGACGACGGGTGCGTTATCAGGATCTACTCAATTACAAAAATCAAA
TTGATACTTTCCGAATGCAAGCTCTTGATGAGCTTACTGCTCAAGCTCAAGAACTAGATATGGGGTACGAATAA
ATGACAGTCAATACATACCAAGCTAGTAGGATTGCTGTACCTACAGAAGAGGATGCTACGCTAGCTAAAAAAAGTAGTCA
AACTTTGGCATCCTATGTACAGGATGATGATCCATGCCGTACTATTAAAGTTGTGCTAGATAACGCTACAAGTGAAACGG
TTACTATACCAGCAGCAGCTTTTCATCTGCTTGTTGACATCTTGACACAAATGGCTAAAGGTAATGCTGTTACTCTTATA
CCCGTACATGCAGAACTCACGACACAAGAAGCAGCTGATATTTTAAATGTTTCTCGTCCTTATTTGGTAGGGTTATTGGA
ATCTGGAGAGATGCCATACCGTAAAGTGGGAACACGACGACGGGTGCGTTATCAGGATCTACTCAATTACAAAAATCAAA
TTGATACTTTCCGAATGCAAGCTCTTGATGAGCTTACTGCTCAAGCTCAAGAACTAGATATGGGGTACGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|