Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2042964..2043104 Replicon chromosome
Accession NZ_HG738868
Organism Serratia marcescens SMB2099

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2043008..2043104 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2042964..2043104 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMB2099_RS09705 2038164..2038589 + 426 WP_033638066.1 RNA polymerase-binding protein DksA -
SMB2099_RS09710 2038782..2039735 + 954 WP_079656425.1 prolyl aminopeptidase -
SMB2099_RS09715 2039767..2039997 - 231 WP_033642715.1 DNA polymerase III subunit theta -
SMB2099_RS09720 2040343..2040861 + 519 WP_025302449.1 non-heme ferritin -
SMB2099_RS09725 2041155..2041571 + 417 WP_046686875.1 CopC domain-containing protein YobA -
SMB2099_RS09730 2041574..2042455 + 882 WP_033646425.1 copper homeostasis membrane protein CopD -
SMB2099_RS09735 2042525..2042866 + 342 WP_025302452.1 YebY family protein -
- 2042964..2043104 - 141 - - Antitoxin
- 2043008..2043104 + 97 - - Toxin
SMB2099_RS09740 2043357..2043761 + 405 WP_033646424.1 hypothetical protein -
SMB2099_RS09745 2043758..2043976 - 219 WP_033638114.1 hypothetical protein -
SMB2099_RS24275 2044040..2044204 - 165 WP_154067227.1 hypothetical protein -
SMB2099_RS09750 2044496..2044846 + 351 WP_033638116.1 DUF4377 domain-containing protein -
SMB2099_RS09755 2045030..2046229 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
SMB2099_RS09760 2046457..2046675 + 219 WP_033646423.1 hypothetical protein -
SMB2099_RS09765 2046847..2047152 + 306 WP_033646422.1 hypothetical protein -
SMB2099_RS09770 2047196..2047531 + 336 WP_033638120.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T285044 NZ_HG738868:2043008-2043104 [Serratia marcescens SMB2099]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT285044 NZ_HG738868:c2043104-2042964 [Serratia marcescens SMB2099]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References