Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 105856..106391 Replicon chromosome
Accession NZ_HG738868
Organism Serratia marcescens SMB2099

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SMB2099_RS00495 Protein ID WP_079656094.1
Coordinates 106116..106391 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SMB2099_RS00490 Protein ID WP_063989142.1
Coordinates 105856..106116 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMB2099_RS00470 101174..101824 + 651 WP_033636562.1 DcrB-related protein -
SMB2099_RS00475 101865..102470 + 606 WP_060452988.1 glutathione S-transferase -
SMB2099_RS00480 102540..103934 + 1395 WP_079656092.1 L-seryl-tRNA(Sec) selenium transferase -
SMB2099_RS00485 103931..105772 + 1842 WP_079656093.1 selenocysteine-specific translation elongation factor -
SMB2099_RS00490 105856..106116 + 261 WP_063989142.1 ribbon-helix-helix domain-containing protein Antitoxin
SMB2099_RS00495 106116..106391 + 276 WP_079656094.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SMB2099_RS00500 106403..107314 - 912 WP_079656095.1 LysR family transcriptional regulator -
SMB2099_RS00505 107436..108062 + 627 WP_079656096.1 LysE family translocator -
SMB2099_RS00510 108116..109363 - 1248 WP_033638635.1 MFS transporter -
SMB2099_RS00515 109581..110573 + 993 WP_033649523.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10550.31 Da        Isoelectric Point: 10.6099

>T285040 WP_079656094.1 NZ_HG738868:106116-106391 [Serratia marcescens SMB2099]
MALKWTSKALSDLARLFEFLALANRTAAANSVKTLVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9721.05 Da        Isoelectric Point: 4.6856

>AT285040 WP_063989142.1 NZ_HG738868:105856-106116 [Serratia marcescens SMB2099]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALTAWLEQEEERRRLTLAALADVEQHNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References