Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3485623..3486292 Replicon chromosome
Accession NZ_HG326223
Organism Serratia marcescens subsp. marcescens Db11

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag SMDB11_RS16305 Protein ID WP_025304123.1
Coordinates 3485623..3486045 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag SMDB11_RS16310 Protein ID WP_004931679.1
Coordinates 3486026..3486292 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMDB11_RS16285 3481512..3482030 + 519 WP_025304119.1 flavodoxin FldB -
SMDB11_RS16290 3482068..3483432 - 1365 WP_025304120.1 cell envelope integrity protein CreD -
SMDB11_RS16295 3483513..3484931 - 1419 WP_025304121.1 two-component system sensor histidine kinase CreC -
SMDB11_RS16300 3484928..3485623 - 696 WP_025304122.1 two-component system response regulator CreB -
SMDB11_RS16305 3485623..3486045 - 423 WP_025304123.1 protein YgfX Toxin
SMDB11_RS16310 3486026..3486292 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
SMDB11_RS16315 3486613..3487605 + 993 WP_025304124.1 tRNA-modifying protein YgfZ -
SMDB11_RS16320 3487644..3488141 - 498 WP_025304125.1 DUF2165 domain-containing protein -
SMDB11_RS16325 3488292..3488966 - 675 WP_025304126.1 hemolysin III family protein -
SMDB11_RS16330 3489150..3489758 + 609 WP_025304127.1 HD domain-containing protein -
SMDB11_RS16335 3489798..3490724 - 927 WP_025304128.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16525.62 Da        Isoelectric Point: 10.8432

>T285000 WP_025304123.1 NZ_HG326223:c3486045-3485623 [Serratia marcescens subsp. marcescens Db11]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGYGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGLLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGNGEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT285000 WP_004931679.1 NZ_HG326223:c3486292-3486026 [Serratia marcescens subsp. marcescens Db11]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References