Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 3477390..3477972 Replicon chromosome
Accession NZ_HG326223
Organism Serratia marcescens subsp. marcescens Db11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SMDB11_RS24540 Protein ID WP_080271268.1
Coordinates 3477390..3477635 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SMDB11_RS16265 Protein ID WP_025304117.1
Coordinates 3477628..3477972 (+) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMDB11_RS16240 3472628..3473938 + 1311 WP_025304116.1 MFS transporter -
SMDB11_RS16250 3474362..3475879 - 1518 WP_004931697.1 lysine--tRNA ligase -
SMDB11_RS24535 3477249..3477380 + 132 WP_080271267.1 type II toxin-antitoxin system RelE/ParE family toxin -
SMDB11_RS24540 3477390..3477635 + 246 WP_080271268.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SMDB11_RS16265 3477628..3477972 + 345 WP_025304117.1 helix-turn-helix domain-containing protein Antitoxin
SMDB11_RS16270 3478023..3479756 - 1734 WP_016929971.1 single-stranded-DNA-specific exonuclease RecJ -
SMDB11_RS16275 3479763..3480479 - 717 WP_025304118.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
SMDB11_RS16280 3480506..3481426 - 921 WP_154747450.1 site-specific tyrosine recombinase XerD -
SMDB11_RS16285 3481512..3482030 + 519 WP_025304119.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-77)

Antitoxin

Cro/C1-type helix-turn-helix domain

(54-91)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9296.60 Da        Isoelectric Point: 9.9223

>T284999 WP_080271268.1 NZ_HG326223:3477390-3477635 [Serratia marcescens subsp. marcescens Db11]
ISLNRGKRGGARSIVAFKRGRHQYFIDGWLKNTVKQNGAKEINDDELATYRELARDFLAMPPEIIKRAIDSGYLREVKCD
D

Download         Length: 246 bp

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12919.85 Da        Isoelectric Point: 11.4121

>AT284999 WP_025304117.1 NZ_HG326223:3477628-3477972 [Serratia marcescens subsp. marcescens Db11]
MTDNRLLRLQKMAQRFNEIGAVSDDTVRNIATRVQAQEQHAQREQHDQMDGARIKMLRRRLGLSQADLAAVVNMSTTSVQ
KWERNAVKPQGAALRMLEIIEQKGVASLIISPRN

Download         Length: 345 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References