Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 3028789..3029351 Replicon chromosome
Accession NZ_HG326223
Organism Serratia marcescens subsp. marcescens Db11

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag SMDB11_RS14185 Protein ID WP_025303801.1
Coordinates 3028789..3029145 (-) Length 119 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A8G2G5I1
Locus tag SMDB11_RS14190 Protein ID WP_004936539.1
Coordinates 3029142..3029351 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMDB11_RS14165 3024525..3025322 - 798 WP_025303797.1 energy transducer TonB -
SMDB11_RS14170 3025425..3026264 - 840 WP_025303798.1 ChaN family lipoprotein -
SMDB11_RS14175 3026442..3027851 + 1410 WP_025303799.1 S-methylmethionine permease -
SMDB11_RS14180 3027841..3028779 + 939 WP_025303800.1 homocysteine S-methyltransferase -
SMDB11_RS14185 3028789..3029145 - 357 WP_025303801.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
SMDB11_RS14190 3029142..3029351 - 210 WP_004936539.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SMDB11_RS14195 3029461..3031740 - 2280 WP_016926766.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
SMDB11_RS24825 3031956..3032129 - 174 WP_038629816.1 hypothetical protein -
SMDB11_RS14205 3032110..3032490 - 381 WP_025303802.1 DUF2570 family protein -
SMDB11_RS14210 3032487..3032888 - 402 WP_025303803.1 M15 family metallopeptidase -
SMDB11_RS14215 3032878..3033204 - 327 WP_004936551.1 phage holin, lambda family -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(27-79)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13163.93 Da        Isoelectric Point: 4.9139

>T284997 WP_025303801.1 NZ_HG326223:c3029145-3028789 [Serratia marcescens subsp. marcescens Db11]
MIFLTAEDIAEFNAEIVPHGRQEGSKVEAVANRVLNAYHYENVTDVYRLAALYLIAISHGHIFLDGNKRTAFQSMALFLG
INGIALREDAELVEITVEAAQGRLNVEQAAEHLRRLTE

Download         Length: 357 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7749.96 Da        Isoelectric Point: 10.1768

>AT284997 WP_004936539.1 NZ_HG326223:c3029351-3029142 [Serratia marcescens subsp. marcescens Db11]
MTTISYTAARNNLAEVLLEAQKQPVEVTRRGHDEVYIISKADYEVLVKAKVKARIQAKHADTIKALANR

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References