Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 8236222..8236892 Replicon chromosome
Accession NC_019678
Organism Rivularia sp. PCC 7116

Toxin (Protein)


Gene name vapB Uniprot ID K9RNL2
Locus tag RIV7116_RS31505 Protein ID WP_015122393.1
Coordinates 8236473..8236892 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID K9RN14
Locus tag RIV7116_RS31500 Protein ID WP_015122392.1
Coordinates 8236222..8236476 (+) Length 85 a.a.

Genomic Context

RIV7116_RS31490RIV7116_RS31500RIV7116_RS31505RIV7116_RS31485RIV7116_RS31495RIV7116_RS31515
Location: 8232413..8233303 (891 bp)
Type: Others
Protein ID: WP_015122390.1
Location: 8236222..8236476 (255 bp)
Type: Antitoxin
Protein ID: WP_015122392.1
Location: 8236473..8236892 (420 bp)
Type: Toxin
Protein ID: WP_015122393.1
Location: 8231241..8232068 (828 bp)
Type: Others
Protein ID: WP_015122389.1
Location: 8233522..8235795 (2274 bp)
Type: Others
Protein ID: WP_015122391.1
Location: 8237846..8241286 (3441 bp)
Type: Others
Protein ID: WP_015122395.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RIV7116_RS314858231241..8232068-828WP_015122389.1alpha/beta hydrolase-
RIV7116_RS314908232413..8233303+891WP_015122390.1LysR family transcriptional regulator-
RIV7116_RS314958233522..8235795-2274WP_015122391.1hypothetical protein-
RIV7116_RS315008236222..8236476+255WP_015122392.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
RIV7116_RS315058236473..8236892+420WP_015122393.1type II toxin-antitoxin system VapC family toxinToxin
RIV7116_RS315158237846..8241286-3441WP_015122395.1virulence factor SrfB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-130)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-67)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16010.70 Da        Isoelectric Point: 5.2702

>T28498 WP_015122393.1 NC_019678:8236473-8236892 [Rivularia sp. PCC 7116]
MKYLLDTCVIYELVAKKPSKKVIDWIDNIEQENIYLSVITIGEIRKGIEKLPESKRKTNLQQWLNDELLIRFQGKILVID
TDVILVWGELTGRLDIEGKRMPAIDSLIAAIAIHNNCSLVTRNEYDFKDVGLSIVNPWQ

Download         Length: 420 bp

>T28498 NC_019678:8236473-8236892 [Rivularia sp. PCC 7116]
ATGAAATATCTGCTCGATACCTGTGTAATTTATGAATTAGTAGCAAAAAAACCTTCCAAAAAAGTTATTGATTGGATTGA
TAATATTGAGCAAGAAAATATTTATTTGAGCGTTATTACTATTGGTGAAATTCGTAAGGGAATAGAGAAACTACCCGAAT
CAAAGCGAAAAACGAATCTTCAACAATGGCTAAACGATGAGTTACTAATACGCTTTCAAGGCAAAATATTGGTAATAGAT
ACAGATGTAATCTTGGTTTGGGGAGAATTAACCGGAAGACTCGATATAGAAGGAAAAAGAATGCCTGCAATTGATTCTTT
AATCGCTGCAATTGCGATACACAATAATTGTAGCTTGGTAACTAGAAATGAATATGATTTTAAGGATGTCGGCTTGAGTA
TTGTTAATCCTTGGCAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9832.14 Da        Isoelectric Point: 4.7174

>AT28498 WP_015122392.1 NC_019678:8236222-8236476 [Rivularia sp. PCC 7116]
MEKYWQLQEAKNKFSEVVDKAINEGAQVITRRGVEVAIVVSYTEYRQMIASKKKISEFFRESPLVEEDLDFSRDKSDARE
DIVL

Download         Length: 255 bp

>AT28498 NC_019678:8236222-8236476 [Rivularia sp. PCC 7116]
ATGGAAAAATATTGGCAGCTACAAGAAGCAAAGAATAAATTTAGTGAAGTGGTAGATAAGGCTATCAATGAAGGAGCACA
AGTTATTACTAGAAGGGGTGTTGAAGTCGCAATAGTTGTATCATATACAGAGTATCGTCAGATGATAGCCTCAAAAAAGA
AGATTTCCGAGTTTTTTCGCGAGTCTCCTTTAGTTGAAGAAGATTTAGATTTTAGTAGGGATAAGAGCGATGCTCGGGAA
GATATTGTATTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBK9RNL2

Antitoxin

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Source
ID
Structure
AlphaFold DBK9RN14

References