Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/Xre(antitoxin)
Location 1705245..1705867 Replicon chromosome
Accession NZ_HG322949
Organism Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628

Toxin (Protein)


Gene name ParT Uniprot ID W0V2T7
Locus tag GJA_RS07255 Protein ID WP_038490472.1
Coordinates 1705245..1705553 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag GJA_RS07260 Protein ID WP_038498979.1
Coordinates 1705550..1705867 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJA_RS07230 1701154..1701729 + 576 WP_038490460.1 elongation factor P -
GJA_RS07235 1701952..1702389 + 438 WP_061301549.1 hypothetical protein -
GJA_RS26020 1702466..1702921 + 456 WP_051780403.1 hypothetical protein -
GJA_RS07245 1703021..1703806 - 786 WP_038490466.1 helix-turn-helix transcriptional regulator -
GJA_RS07250 1703995..1705152 + 1158 WP_197539828.1 MFS transporter -
GJA_RS07255 1705245..1705553 - 309 WP_038490472.1 RES family NAD+ phosphorylase Toxin
GJA_RS07260 1705550..1705867 - 318 WP_038498979.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
GJA_RS07265 1706207..1708282 - 2076 WP_038490475.1 AAA family ATPase -
GJA_RS27965 1708788..1708982 - 195 WP_174525960.1 hypothetical protein -
GJA_RS07275 1709291..1710262 + 972 WP_038490477.1 ornithine cyclodeaminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(37-89)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(57-102)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 10901.38 Da        Isoelectric Point: 7.4015

>T284978 WP_038490472.1 NZ_HG322949:c1705553-1705245 [Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628]
MTVALWRIAATTATYEANDLSGTGAKHTGGRWNPVGWDANPAGMTSVQAGEAWLKGKASALLVVPSVIVPEESNILINPL
HPDAAAITATPLRKWHHDARYF

Download         Length: 309 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11349.04 Da        Isoelectric Point: 6.2980

>AT284978 WP_038498979.1 NZ_HG322949:c1705867-1705550 [Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628]
MPKEALMDSLGLSRATINRKVLRAQPLSREESERVVGMQSLIGQVQAMIDADSAPDFDAARWLARWLAEPLPVLGGNTPG
SYISTVEGQKYVGKLLAMTQSGAYA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W0V2T7

Antitoxin

Source ID Structure

References