Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4205996..4206715 Replicon chromosome
Accession NZ_HF571988
Organism Yersinia enterocolitica (type O:5) str. YE53/03 isolate host faecal sample

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag YE5303_RS19550 Protein ID WP_046051652.1
Coordinates 4205996..4206316 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag YE5303_RS19555 Protein ID WP_046051653.1
Coordinates 4206350..4206715 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YE5303_RS19530 4201965..4202900 + 936 Protein_3813 DNA-protecting protein DprA -
YE5303_RS19535 4203192..4204304 - 1113 WP_072084067.1 IS3 family transposase -
YE5303_RS19545 4205046..4205882 - 837 WP_046051651.1 DUF4942 domain-containing protein -
YE5303_RS19550 4205996..4206316 - 321 WP_046051652.1 TA system toxin CbtA family protein Toxin
YE5303_RS19555 4206350..4206715 - 366 WP_046051653.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
YE5303_RS23705 4206747..4206968 - 222 WP_080342212.1 DUF987 domain-containing protein -
YE5303_RS19560 4206977..4207447 - 471 WP_046051654.1 DNA repair protein RadC -
YE5303_RS19565 4207518..4208339 - 822 WP_046051655.1 DUF945 domain-containing protein -
YE5303_RS19570 4208415..4208855 - 441 WP_046051656.1 hypothetical protein -
YE5303_RS19575 4208891..4209070 - 180 WP_046051657.1 hypothetical protein -
YE5303_RS19580 4209121..4209924 - 804 WP_046051658.1 hypothetical protein -
YE5303_RS19585 4209944..4210378 - 435 WP_046051659.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 4203192..4204304 1112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(18-116)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12080.80 Da        Isoelectric Point: 5.9538

>T284952 WP_046051652.1 NZ_HF571988:c4206316-4205996 [Yersinia enterocolitica (type O:5) str. YE53/03]
MHISTVPATVPVSPRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDSAIQEHIEAGITLADAVNFLVERYELIRTDRKGF
TWQDQTPFLAAIDILRARRATGLMNI

Download         Length: 321 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13578.39 Da        Isoelectric Point: 5.5403

>AT284952 WP_046051653.1 NZ_HF571988:c4206715-4206350 [Yersinia enterocolitica (type O:5) str. YE53/03]
MQSTTLSGTSAENASCLQWGLKRNITPCFCARLVQEGNRLYFLADRAGFDGSFSDDEALRLDQVFPLMMKQLERMLTTGE
LDPRCQHCVTLHHNELTCEADTLGSHGYVYIAIYPQSAVTR

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References