Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3599113..3599258 Replicon chromosome
Accession NZ_FO834906
Organism Klebsiella pneumoniae strain Kp52.145

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3599120..3599222 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3599113..3599258 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN49_RS19260 3594645..3596078 + 1434 WP_016529029.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BN49_RS19265 3596194..3596433 + 240 WP_002911393.1 YebV family protein -
BN49_RS19270 3596531..3596722 + 192 WP_002911395.1 YebW family protein -
BN49_RS19275 3596719..3597372 - 654 WP_016529030.1 protein-serine/threonine phosphatase -
BN49_RS19280 3597529..3598497 + 969 WP_004151446.1 VirK/YbjX family protein -
BN49_RS30735 3598602..3598745 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3599113..3599258 + 146 - - Antitoxin
- 3599120..3599222 - 103 - - Toxin
BN49_RS19290 3599381..3599719 - 339 WP_016529031.1 YebY family protein -
BN49_RS19295 3599736..3600605 - 870 WP_004184661.1 copper homeostasis membrane protein CopD -
BN49_RS19300 3600609..3600983 - 375 WP_016529032.1 CopC domain-containing protein YobA -
BN49_RS19305 3601096..3601326 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BN49_RS19310 3601405..3602064 + 660 WP_002911407.1 exodeoxyribonuclease X -
BN49_RS19315 3602068..3604128 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T284932 NZ_FO834906:c3599222-3599120 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT284932 NZ_FO834906:3599113-3599258 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References