Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 61467..62002 Replicon plasmid megaplasmid
Accession NZ_FO818638
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name relE Uniprot ID A0A0B6XFT9
Locus tag XBW1_RS21700 Protein ID WP_046338210.1
Coordinates 61715..62002 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0B6XF40
Locus tag XBW1_RS21695 Protein ID WP_046338209.1
Coordinates 61467..61718 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XBW1_RS24990 56641..58314 + 1674 WP_052726130.1 hypothetical protein -
XBW1_RS21680 58348..59379 + 1032 WP_046338206.1 hypothetical protein -
XBW1_RS21685 59567..59761 - 195 WP_046338207.1 host cell division inhibitor Icd-like protein -
XBW1_RS24995 59731..60054 - 324 Protein_63 ash family protein -
XBW1_RS21690 60389..61321 + 933 WP_046338208.1 hypothetical protein -
XBW1_RS21695 61467..61718 + 252 WP_046338209.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XBW1_RS21700 61715..62002 + 288 WP_046338210.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XBW1_RS25000 62110..62325 - 216 WP_155399215.1 hypothetical protein -
XBW1_RS25005 62367..62888 - 522 WP_155399220.1 CPBP family intramembrane metalloprotease -
XBW1_RS21710 63147..63416 - 270 WP_046338211.1 PAAR domain-containing protein -
XBW1_RS21715 63400..64629 - 1230 WP_046338212.1 DUF3396 domain-containing protein -
XBW1_RS22635 64619..66193 - 1575 WP_052726132.1 VRR-NUC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..177250 177250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.27 Da        Isoelectric Point: 10.5432

>T284918 WP_046338210.1 NZ_FO818638:61715-62002 [Xenorhabdus bovienii]
VIYKIKFREDALKEWNKLDKAILKQFAKKLKKCCENPRIPSAKLRGMSDCYKIKLRASGFRLVYQIIDDQLIIAVIAVGK
RERSDVYNLASERLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9316.65 Da        Isoelectric Point: 3.9150

>AT284918 WP_046338209.1 NZ_FO818638:61467-61718 [Xenorhabdus bovienii]
MANLILSDTSASISELKKNPMATVNAGAGYPVAILNRNQPAFYCIPAELYEMMLDTIDDQELVRLVKERENQPLIDVDLD
EYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B6XFT9

Antitoxin

Source ID Structure
AlphaFold DB A0A0B6XF40

References