Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4602955..4603998 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name PP_4152 Uniprot ID A0A077N2M7
Locus tag XBW1_RS21215 Protein ID WP_038216484.1
Coordinates 4602955..4603530 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A0B6XE00
Locus tag XBW1_RS21220 Protein ID WP_046337773.1
Coordinates 4603534..4603998 (-) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XBW1_RS21200 4598903..4600300 - 1398 Protein_4205 L-seryl-tRNA(Sec) selenium transferase -
XBW1_RS21205 4600318..4601190 - 873 WP_046337771.1 formate dehydrogenase accessory protein FdhE -
XBW1_RS25230 4601818..4602040 - 223 Protein_4207 IS982 family transposase -
XBW1_RS21210 4602082..4602627 - 546 WP_046337772.1 hypothetical protein -
XBW1_RS21215 4602955..4603530 - 576 WP_038216484.1 PIN domain-containing protein Toxin
XBW1_RS21220 4603534..4603998 - 465 WP_046337773.1 helix-turn-helix domain-containing protein Antitoxin
XBW1_RS21225 4604306..4604665 - 360 WP_046337774.1 hypothetical protein -
XBW1_RS21230 4604668..4605309 - 642 WP_046337775.1 formate dehydrogenase cytochrome b556 subunit -
XBW1_RS21235 4605306..4606214 - 909 Protein_4213 formate dehydrogenase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21800.25 Da        Isoelectric Point: 4.6565

>T284916 WP_038216484.1 NZ_FO818637:c4603530-4602955 [Xenorhabdus bovienii]
MQHSPYPAVLDACVLYPARLRDLLMHLGLAGLYQPKWSDTIQDEWKRNLLKQRSDIKPEVLEQTTILMNTALPDANVTGF
ELLIEGFRLPDEDDRHVLATAIRANAEVIVTMNLKDFPPQILAEFDIEALHPDEFISDLFDLNHAAALEAVRQQRIALKN
PPMSTDEFLYMLLKQGLPMTVKAIDAYRFMV

Download         Length: 576 bp

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17117.71 Da        Isoelectric Point: 6.6083

>AT284916 WP_046337773.1 NZ_FO818637:c4603998-4603534 [Xenorhabdus bovienii]
MNNTTLTSLNLPAQHEIEIAMRGQRELATFLSTKSETQQIIINGADNVSHQIELPTSVLTMLMNILGELAVGNAVQIVPV
HAELTTQEAANIMNVSRPHMVKLLEDGKLPHHKTGRHRRVLFAELMEYKKKRDADSIAAMQELAAQAQELNLGY

Download         Length: 465 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A077N2M7

Antitoxin

Source ID Structure
AlphaFold DB A0A0B6XE00

References