Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4142835..4143471 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name vapC Uniprot ID A0A0B6XDE4
Locus tag XBW1_RS18940 Protein ID WP_046337596.1
Coordinates 4142835..4143239 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XBW1_RS18945 Protein ID WP_196244143.1
Coordinates 4143232..4143471 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XBW1_RS18920 4138962..4139702 + 741 WP_046337592.1 SDR family oxidoreductase -
XBW1_RS18925 4139865..4139975 - 111 Protein_3773 PTS sugar transporter subunit IIB -
XBW1_RS18930 4140279..4141661 - 1383 WP_046337593.1 IS4 family transposase -
XBW1_RS18935 4141935..4142630 + 696 WP_046337595.1 IS6 family transposase -
XBW1_RS18940 4142835..4143239 - 405 WP_046337596.1 tRNA(fMet)-specific endonuclease VapC Toxin
XBW1_RS18945 4143232..4143471 - 240 WP_196244143.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
XBW1_RS24870 4143547..4143837 - 291 WP_155399172.1 hypothetical protein -
XBW1_RS18955 4144626..4145012 + 387 WP_046337598.1 VOC family protein -
XBW1_RS18960 4145077..4147821 + 2745 WP_046337599.1 CRISPR-associated helicase/endonuclease Cas3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4136395..4145012 8617


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15217.58 Da        Isoelectric Point: 9.7971

>T284915 WP_046337596.1 NZ_FO818637:c4143239-4142835 [Xenorhabdus bovienii]
MIKYLLDTNIVIFTIKRKPESLLPKFNQHTNQLAISAITLAELIFGAEKSMNPTKNLATVNDFVSRLTVLPYDEQAAFHY
GDIRAILEKKGKRIGDNDLHIAAHARSKGLIVVTNNTREFERVDGLRIEDWTKP

Download         Length: 405 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9103.07 Da        Isoelectric Point: 4.5105

>AT284915 WP_196244143.1 NZ_FO818637:c4143471-4143232 [Xenorhabdus bovienii]
IQQGKVFMSNRTQNVRLPADTRFPDNVKEVIVRVSGKERIISPVQNAWDSFFLSDQSVTDDFLPNRADQITSERESFDD

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B6XDE4

Antitoxin

Source ID Structure

References