Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 879580..880199 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name Hha Uniprot ID N1NUC1
Locus tag XBW1_RS04185 Protein ID WP_010845060.1
Coordinates 879996..880199 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A077MYD9
Locus tag XBW1_RS04180 Protein ID WP_038191932.1
Coordinates 879580..879948 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XBW1_RS04170 874614..875813 + 1200 WP_038191927.1 efflux RND transporter periplasmic adaptor subunit -
XBW1_RS04175 875829..878978 + 3150 WP_046336035.1 multidrug efflux RND transporter permease subunit -
XBW1_RS04180 879580..879948 + 369 WP_038191932.1 Hha toxicity modulator TomB Antitoxin
XBW1_RS04185 879996..880199 + 204 WP_010845060.1 hemolysin expression modulator Hha Toxin
XBW1_RS23805 881186..881892 + 707 WP_155399055.1 IS1 family transposase -
XBW1_RS04200 881918..882418 + 501 WP_082243297.1 thioesterase family protein -
XBW1_RS04205 882476..883768 - 1293 WP_046336037.1 ammonium transporter AmtB -
XBW1_RS04210 883784..884122 - 339 WP_038191938.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8077.34 Da        Isoelectric Point: 6.9770

>T284911 WP_010845060.1 NZ_FO818637:879996-880199 [Xenorhabdus bovienii]
MTKTDYLMRLRKCTSIETLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPSSVWKFVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14485.34 Da        Isoelectric Point: 4.9443

>AT284911 WP_038191932.1 NZ_FO818637:879580-879948 [Xenorhabdus bovienii]
MDEYSPRRHDIVELKYLCENLIHEAFSVLNRADNHWINDLTSEKSLKLNELIEHIAAFVWSFKIKYADNYNLSTLIDEYL
DETYNLFGSDKISFFELTKWQKTNEHLTNILLHDLNACLSKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB N1NUC1

Antitoxin

Source ID Structure
AlphaFold DB A0A077MYD9

References