Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 787698..788229 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name relE Uniprot ID A0A0B6X4T9
Locus tag XBW1_RS03630 Protein ID WP_046335942.1
Coordinates 787698..787979 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A077NTI0
Locus tag XBW1_RS03635 Protein ID WP_038216894.1
Coordinates 787966..788229 (-) Length 88 a.a.

Genomic Context

XBW1_RS03650XBW1_RS03595XBW1_RS03600XBW1_RS03605XBW1_RS03610XBW1_RS03615XBW1_RS03620XBW1_RS03625XBW1_RS03630XBW1_RS03635XBW1_RS03640XBW1_RS03645XBW1_RS23795XBW1_RS03655XBW1_RS03660XBW1_RS03665
Location: 790400..790840 (441 bp)
Type: Others
Protein ID: WP_046335944.1
Location: 782930..783583 (654 bp)
Type: Others
Protein ID: WP_038216874.1
Location: 783576..784700 (1125 bp)
Type: Others
Protein ID: WP_046335937.1
Location: 784684..785043 (360 bp)
Type: Others
Protein ID: WP_038216878.1
Location: 785040..785705 (666 bp)
Type: Others
Protein ID: WP_046335938.1
Location: 785683..786531 (849 bp)
Type: Others
Protein ID: WP_046335939.1
Location: 786506..786844 (339 bp)
Type: Others
Protein ID: WP_046335940.1
Location: 786841..787596 (756 bp)
Type: Others
Protein ID: WP_046335941.1
Location: 787698..787979 (282 bp)
Type: Toxin
Protein ID: WP_046335942.1
Location: 787966..788229 (264 bp)
Type: Antitoxin
Protein ID: WP_038216894.1
Location: 788348..788911 (564 bp)
Type: Others
Protein ID: WP_082243293.1
Location: 789159..789917 (759 bp)
Type: Others
Protein ID: WP_046335943.1
Location: 790106..790276 (171 bp)
Type: Others
Protein ID: WP_080718388.1
Location: 791264..791617 (354 bp)
Type: Others
Protein ID: WP_038215239.1
Location: 791614..791916 (303 bp)
Type: Others
Protein ID: WP_038215241.1
Location: 792185..792472 (288 bp)
Type: Others
Protein ID: WP_155399069.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XBW1_RS03595782930..783583-654WP_038216874.1DUF2612 domain-containing protein-
XBW1_RS03600783576..784700-1125WP_046335937.1baseplate J/gp47 family protein-
XBW1_RS03605784684..785043-360WP_038216878.1hypothetical protein-
XBW1_RS03610785040..785705-666WP_046335938.1hypothetical protein-
XBW1_RS03615785683..786531-849WP_046335939.1hypothetical protein-
XBW1_RS03620786506..786844-339WP_046335940.1hypothetical protein-
XBW1_RS03625786841..787596-756WP_046335941.1hypothetical protein-
XBW1_RS03630787698..787979-282WP_046335942.1type II toxin-antitoxin system YafQ family toxinToxin
XBW1_RS03635787966..788229-264WP_038216894.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
XBW1_RS03640788348..788911-564WP_082243293.1phage antirepressor N-terminal domain-containing protein-
XBW1_RS03645789159..789917-759WP_046335943.1antirepressor-
XBW1_RS23795790106..790276-171WP_080718388.1Arc family DNA-binding protein-
XBW1_RS03650790400..790840+441WP_046335944.1Arc family DNA-binding protein-
XBW1_RS03655791264..791617-354WP_038215239.1hypothetical protein-
XBW1_RS03660791614..791916-303WP_038215241.1hypothetical protein-
XBW1_RS03665792185..792472-288WP_155399069.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--750328..82942079092


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10894.41 Da        Isoelectric Point: 6.8614

>T284910 WP_046335942.1 NZ_FO818637:c787979-787698 [Xenorhabdus bovienii]
MRTTDYTSQFKRDYKREKKGRHRETLDDALMTVTELLASDSLLEPKYCDHALSGDWKDFRDCHIKPDLILIYQKPDADIL
RLVRLGSHSELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9305.83 Da        Isoelectric Point: 5.0490

>AT284910 WP_038216894.1 NZ_FO818637:c788229-787966 [Xenorhabdus bovienii]
MATNQLIQTRIDGEIKAEAAAVLAAMGLTVSDAVRMMLTRVARDKILPFEPLIPNETTIAAMKEARKGGGKSFSSVKDLM
ADLNADD

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0B6X4T9

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A077NTI0

References