Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
| Location | 1925642..1926336 | Replicon | chromosome |
| Accession | NC_019675 | ||
| Organism | Cyanobium gracile PCC 6307 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | K9P8R1 |
| Locus tag | CYAGR_RS18355 | Protein ID | WP_015109561.1 |
| Coordinates | 1925884..1926336 (+) | Length | 151 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | K9P7L9 |
| Locus tag | CYAGR_RS18350 | Protein ID | WP_015109560.1 |
| Coordinates | 1925642..1925887 (+) | Length | 82 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CYAGR_RS09315 | 1921229..1921459 | + | 231 | WP_015109551.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| CYAGR_RS09320 | 1921459..1921860 | + | 402 | WP_015109552.1 | PIN domain-containing protein | - |
| CYAGR_RS09325 | 1922146..1922394 | + | 249 | WP_015109553.1 | hypothetical protein | - |
| CYAGR_RS09330 | 1922391..1922798 | + | 408 | WP_015109554.1 | type II toxin-antitoxin system VapC family toxin | - |
| CYAGR_RS09335 | 1922799..1923167 | - | 369 | WP_015109555.1 | hypothetical protein | - |
| CYAGR_RS09340 | 1923261..1923545 | + | 285 | WP_015109556.1 | DUF1778 domain-containing protein | - |
| CYAGR_RS09345 | 1923542..1924060 | + | 519 | WP_015109557.1 | hypothetical protein | - |
| CYAGR_RS18340 | 1924295..1924486 | - | 192 | WP_015109558.1 | hypothetical protein | - |
| CYAGR_RS18345 | 1924552..1924665 | - | 114 | WP_156818592.1 | DUF3387 domain-containing protein | - |
| CYAGR_RS09355 | 1924928..1925620 | + | 693 | WP_015109559.1 | hypothetical protein | - |
| CYAGR_RS18350 | 1925642..1925887 | + | 246 | WP_015109560.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
| CYAGR_RS18355 | 1925884..1926336 | + | 453 | WP_015109561.1 | PIN domain-containing protein | Toxin |
| CYAGR_RS09370 | 1926336..1927007 | + | 672 | WP_015109562.1 | pyridoxamine 5'-phosphate oxidase | - |
| CYAGR_RS09375 | 1927108..1928229 | + | 1122 | WP_015109563.1 | MBL fold metallo-hydrolase | - |
| CYAGR_RS09380 | 1928286..1928816 | + | 531 | WP_015109564.1 | rhodanese-like domain-containing protein | - |
| CYAGR_RS09385 | 1928787..1929449 | - | 663 | WP_015109565.1 | methyltransferase domain-containing protein | - |
| CYAGR_RS09390 | 1929497..1930660 | + | 1164 | WP_015109566.1 | exonuclease SbcCD subunit D | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 151 a.a. Molecular weight: 15880.21 Da Isoelectric Point: 6.5802
>T28491 WP_015109561.1 NC_019675:1925884-1926336 [Cyanobium gracile PCC 6307]
VSAALLDVNVLIALLDGRHVHHEQAHDWFAASEDLGWATCPLTQNAVLRILGQPRYPNSPGPPAVVAPLMRELIRHPRHH
FWPDAISLLAAPGGEAPLVDATQLLEAGQVTDTYLLALAVHHGGTLVSLDRRLGSGAVAGGSAALRLIPT
VSAALLDVNVLIALLDGRHVHHEQAHDWFAASEDLGWATCPLTQNAVLRILGQPRYPNSPGPPAVVAPLMRELIRHPRHH
FWPDAISLLAAPGGEAPLVDATQLLEAGQVTDTYLLALAVHHGGTLVSLDRRLGSGAVAGGSAALRLIPT
Download Length: 453 bp
>T28491 NC_019675:1925884-1926336 [Cyanobium gracile PCC 6307]
GTGAGCGCAGCCCTGCTGGATGTGAACGTGCTGATCGCCCTGCTGGACGGGCGCCACGTGCACCATGAGCAGGCCCACGA
CTGGTTCGCCGCCTCCGAGGACCTGGGCTGGGCCACCTGCCCGCTCACCCAGAACGCGGTGCTGCGGATCCTCGGCCAGC
CCCGCTACCCCAACAGCCCGGGGCCACCGGCGGTGGTGGCGCCCTTGATGCGGGAGCTGATCCGCCATCCACGCCACCAC
TTCTGGCCCGATGCCATCAGCCTGCTTGCCGCGCCGGGGGGCGAAGCTCCGCTGGTCGACGCCACCCAGCTGCTGGAGGC
GGGGCAAGTCACCGACACCTATCTGTTGGCGCTGGCGGTGCACCACGGCGGCACGCTGGTGAGTCTCGACCGCCGCCTGG
GCTCCGGGGCCGTGGCGGGCGGCAGCGCCGCCCTGCGCCTGATCCCCACCTGA
GTGAGCGCAGCCCTGCTGGATGTGAACGTGCTGATCGCCCTGCTGGACGGGCGCCACGTGCACCATGAGCAGGCCCACGA
CTGGTTCGCCGCCTCCGAGGACCTGGGCTGGGCCACCTGCCCGCTCACCCAGAACGCGGTGCTGCGGATCCTCGGCCAGC
CCCGCTACCCCAACAGCCCGGGGCCACCGGCGGTGGTGGCGCCCTTGATGCGGGAGCTGATCCGCCATCCACGCCACCAC
TTCTGGCCCGATGCCATCAGCCTGCTTGCCGCGCCGGGGGGCGAAGCTCCGCTGGTCGACGCCACCCAGCTGCTGGAGGC
GGGGCAAGTCACCGACACCTATCTGTTGGCGCTGGCGGTGCACCACGGCGGCACGCTGGTGAGTCTCGACCGCCGCCTGG
GCTCCGGGGCCGTGGCGGGCGGCAGCGCCGCCCTGCGCCTGATCCCCACCTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8512.79 Da Isoelectric Point: 11.6549
>AT28491 WP_015109560.1 NC_019675:1925642-1925887 [Cyanobium gracile PCC 6307]
MRTTLQLDDDVLAAARVLARQRRTSLGAVISALARQGLVAPPPGTASSGPSHRNGLPLLPWQPQGAPVDLALVNSLRDEL
P
MRTTLQLDDDVLAAARVLARQRRTSLGAVISALARQGLVAPPPGTASSGPSHRNGLPLLPWQPQGAPVDLALVNSLRDEL
P
Download Length: 246 bp
>AT28491 NC_019675:1925642-1925887 [Cyanobium gracile PCC 6307]
ATGCGCACCACCCTGCAGCTCGATGACGACGTGCTGGCGGCGGCCCGGGTGCTGGCCCGGCAGCGGCGCACCAGCCTCGG
GGCCGTGATCAGTGCGCTGGCCCGCCAAGGGCTGGTGGCTCCACCCCCCGGCACCGCCAGCAGCGGTCCCAGCCACCGCA
ACGGGTTGCCCCTGCTGCCCTGGCAGCCGCAGGGCGCGCCGGTGGACCTCGCACTCGTCAACAGCTTGCGCGACGAGCTG
CCGTGA
ATGCGCACCACCCTGCAGCTCGATGACGACGTGCTGGCGGCGGCCCGGGTGCTGGCCCGGCAGCGGCGCACCAGCCTCGG
GGCCGTGATCAGTGCGCTGGCCCGCCAAGGGCTGGTGGCTCCACCCCCCGGCACCGCCAGCAGCGGTCCCAGCCACCGCA
ACGGGTTGCCCCTGCTGCCCTGGCAGCCGCAGGGCGCGCCGGTGGACCTCGCACTCGTCAACAGCTTGCGCGACGAGCTG
CCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|