Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 323235..323772 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name relE Uniprot ID A0A077N389
Locus tag XBW1_RS01455 Protein ID WP_038194741.1
Coordinates 323235..323528 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A077MRP5
Locus tag XBW1_RS01460 Protein ID WP_038194743.1
Coordinates 323518..323772 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XBW1_RS01435 319399..319938 + 540 WP_038207233.1 pyridoxamine 5'-phosphate oxidase family protein -
XBW1_RS01440 320295..320525 + 231 WP_012986782.1 ferrous iron transporter A -
XBW1_RS01445 320590..322902 + 2313 WP_046337811.1 Fe(2+) transporter permease subunit FeoB -
XBW1_RS01450 322912..323151 + 240 WP_038194739.1 ferrous iron transporter C -
XBW1_RS01455 323235..323528 - 294 WP_038194741.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XBW1_RS01460 323518..323772 - 255 WP_038194743.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
XBW1_RS01465 324068..324511 + 444 WP_046335667.1 OsmC family protein -
XBW1_RS01470 324558..325334 - 777 WP_038197660.1 pimeloyl-ACP methyl ester esterase BioH -
XBW1_RS01475 325373..326056 + 684 WP_046335669.1 DNA utilization protein GntX -
XBW1_RS01480 326129..326704 + 576 WP_038197662.1 Fe-S biogenesis protein NfuA -
XBW1_RS01485 326869..327192 + 324 WP_038181767.1 thiosulfate sulfurtransferase GlpE -
XBW1_RS01490 327266..328099 + 834 WP_038197663.1 rhomboid family intramembrane serine protease GlpG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11498.47 Da        Isoelectric Point: 10.1538

>T284909 WP_038194741.1 NZ_FO818637:c323528-323235 [Xenorhabdus bovienii]
MKFNIDFDERALKEWHKLDKSIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRSSGFRLVYQVIDEEIVIWVIAVG
KREDSMAYDIAKKRLGV

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9748.09 Da        Isoelectric Point: 4.6952

>AT284909 WP_038194743.1 NZ_FO818637:c323772-323518 [Xenorhabdus bovienii]
MSTIQVRVDEDLKKASYKAFEKLNVSPSDALRLFLRYVAENEKLPFSEVSLIVAENDNDEDILDVVRERIRNPAKRVRVN
LDEI

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A077N389

Antitoxin

Source ID Structure
AlphaFold DB A0A077MRP5

References