Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 158439..158989 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name parE Uniprot ID A0A077PME5
Locus tag XBW1_RS00735 Protein ID WP_038197671.1
Coordinates 158699..158989 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A077MZK9
Locus tag XBW1_RS00730 Protein ID WP_038197673.1
Coordinates 158439..158711 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XBW1_RS00710 153738..154514 - 777 WP_046335570.1 phenylacetate-CoA oxygenase subunit PaaC -
XBW1_RS00715 154525..154812 - 288 WP_038207257.1 1,2-phenylacetyl-CoA epoxidase subunit B -
XBW1_RS00720 154857..155798 - 942 WP_038197674.1 1,2-phenylacetyl-CoA epoxidase subunit A -
XBW1_RS00725 156126..158198 + 2073 WP_046337796.1 phenylacetic acid degradation bifunctional protein PaaZ -
XBW1_RS00730 158439..158711 + 273 WP_038197673.1 CopG family ribbon-helix-helix protein Antitoxin
XBW1_RS00735 158699..158989 + 291 WP_038197671.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XBW1_RS23710 158991..159312 - 322 Protein_143 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
XBW1_RS00740 159309..159845 - 537 WP_038207251.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
XBW1_RS00745 159939..160977 - 1039 Protein_145 IS630 family transposase -
XBW1_RS00750 161670..162764 - 1095 WP_046335571.1 aminotransferase class V-fold PLP-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10918.59 Da        Isoelectric Point: 9.4808

>T284908 WP_038197671.1 NZ_FO818637:158699-158989 [Xenorhabdus bovienii]
MPRLIWSPAALTDVQKLYRFLVNKDEAAARRAIKTIRASVKILAHQPEVGRPAEDMDPVFREWLIDFGSSGYIALYRFDG
ETATILAVRHQKEAGY

Download         Length: 291 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10663.88 Da        Isoelectric Point: 4.6617

>AT284908 WP_038197673.1 NZ_FO818637:158439-158711 [Xenorhabdus bovienii]
MATSVKLDDNLKSRIQHLAEVRQRSAHWIMREAIRDYVEREEKRESFKQDALRAWEAYQENGLHLTLEEADDWLVKLEAG
DDTELPECHV

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A077PME5

Antitoxin

Source ID Structure
AlphaFold DB A0A077MZK9

References