Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 158439..158989 Replicon chromosome
Accession NZ_FO818637
Organism Xenorhabdus bovienii strain CS03

Toxin (Protein)


Gene name parE Uniprot ID A0A077PME5
Locus tag XBW1_RS00735 Protein ID WP_038197671.1
Coordinates 158699..158989 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A077MZK9
Locus tag XBW1_RS00730 Protein ID WP_038197673.1
Coordinates 158439..158711 (+) Length 91 a.a.

Genomic Context

XBW1_RS00725XBW1_RS00730XBW1_RS00735XBW1_RS00710XBW1_RS00715XBW1_RS00720XBW1_RS23710XBW1_RS00740XBW1_RS00745XBW1_RS00750
Location: 156126..158198 (2073 bp)
Type: Others
Protein ID: WP_046337796.1
Location: 158439..158711 (273 bp)
Type: Antitoxin
Protein ID: WP_038197673.1
Location: 158699..158989 (291 bp)
Type: Toxin
Protein ID: WP_038197671.1
Location: 153738..154514 (777 bp)
Type: Others
Protein ID: WP_046335570.1
Location: 154525..154812 (288 bp)
Type: Others
Protein ID: WP_038207257.1
Location: 154857..155798 (942 bp)
Type: Others
Protein ID: WP_038197674.1
Location: 158991..159312 (322 bp)
Type: Others
Protein ID: Protein_143
Location: 159309..159845 (537 bp)
Type: Others
Protein ID: WP_038207251.1
Location: 159939..160977 (1039 bp)
Type: Others
Protein ID: Protein_145
Location: 161670..162764 (1095 bp)
Type: Others
Protein ID: WP_046335571.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XBW1_RS00710153738..154514-777WP_046335570.1phenylacetate-CoA oxygenase subunit PaaC-
XBW1_RS00715154525..154812-288WP_038207257.11,2-phenylacetyl-CoA epoxidase subunit B-
XBW1_RS00720154857..155798-942WP_038197674.11,2-phenylacetyl-CoA epoxidase subunit A-
XBW1_RS00725156126..158198+2073WP_046337796.1phenylacetic acid degradation bifunctional protein PaaZ-
XBW1_RS00730158439..158711+273WP_038197673.1CopG family ribbon-helix-helix proteinAntitoxin
XBW1_RS00735158699..158989+291WP_038197671.1type II toxin-antitoxin system RelE/ParE family toxinToxin
XBW1_RS23710158991..159312-322Protein_143nucleotidyl transferase AbiEii/AbiGii toxin family protein-
XBW1_RS00740159309..159845-537WP_038207251.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein-
XBW1_RS00745159939..160977-1039Protein_145IS630 family transposase-
XBW1_RS00750161670..162764-1095WP_046335571.1aminotransferase class V-fold PLP-dependent enzyme-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10918.59 Da        Isoelectric Point: 9.4808

>T284908 WP_038197671.1 NZ_FO818637:158699-158989 [Xenorhabdus bovienii]
MPRLIWSPAALTDVQKLYRFLVNKDEAAARRAIKTIRASVKILAHQPEVGRPAEDMDPVFREWLIDFGSSGYIALYRFDG
ETATILAVRHQKEAGY

Download         Length: 291 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10663.88 Da        Isoelectric Point: 4.6617

>AT284908 WP_038197673.1 NZ_FO818637:158439-158711 [Xenorhabdus bovienii]
MATSVKLDDNLKSRIQHLAEVRQRSAHWIMREAIRDYVEREEKRESFKQDALRAWEAYQENGLHLTLEEADDWLVKLEAG
DDTELPECHV

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A077PME5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A077MZK9

References