Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2313075..2313868 Replicon chromosome
Accession NZ_FO704551
Organism Xenorhabdus poinarii G6

Toxin (Protein)


Gene name TacT2 Uniprot ID A0A068R4R5
Locus tag XPG1_RS10705 Protein ID WP_045959072.1
Coordinates 2313356..2313868 (+) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag XPG1_RS10700 Protein ID WP_045960678.1
Coordinates 2313075..2313359 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XPG1_RS10675 2308125..2308553 + 429 WP_045959067.1 EamA family transporter -
XPG1_RS10680 2308673..2310313 - 1641 WP_045959068.1 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) -
XPG1_RS10685 2310428..2310961 - 534 WP_045959069.1 replication initiation negative regulator SeqA -
XPG1_RS10690 2311232..2312011 + 780 WP_045959070.1 esterase -
XPG1_RS10695 2312203..2312940 + 738 WP_045959071.1 class I SAM-dependent methyltransferase -
XPG1_RS10700 2313075..2313359 + 285 WP_045960678.1 DUF1778 domain-containing protein Antitoxin
XPG1_RS10705 2313356..2313868 + 513 WP_045959072.1 GNAT family N-acetyltransferase Toxin
XPG1_RS10710 2313937..2314764 - 828 WP_045959073.1 histidinol-phosphate aminotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-146)

Antitoxin

Vibrio phage ICP1, Orf50

(13-86)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18658.78 Da        Isoelectric Point: 8.5068

>T284906 WP_045959072.1 NZ_FO704551:2313356-2313868 [Xenorhabdus poinarii G6]
MTVNLTEPEPLQHSHSIEAFCSGEESLDHWLKTRAMANQRSRASRTFVTCIDNQVMGYYALSTGVITTSQAVGRFKRNMP
SDIPIILLGRLAVDVKAKGMGIGRALVKDAALRVLQASGLVGVRGMVVHALSEEAKRFYEYIGFVPSPIDPMMLMITLTD
LQLAMGIHPN

Download         Length: 513 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10665.38 Da        Isoelectric Point: 10.5359

>AT284906 WP_045960678.1 NZ_FO704551:2313075-2313359 [Xenorhabdus poinarii G6]
MKKPETTVARSTLNLRIKPEDKILLDRAANSVGKNRTEFILEAVRRAAEETLADLRVIKVSPEVYQAFVAQLDAPPRSNE
ALRKTMMSKSPWEK

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068R4R5

Antitoxin

Source ID Structure

References