Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 3627619..3628264 Replicon chromosome
Accession NZ_FO704550
Organism Xenorhabdus doucetiae strain FRM16

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag XDD1_RS19690 Protein ID WP_038268917.1
Coordinates 3628088..3628264 (-) Length 59 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag XDD1_RS15795 Protein ID WP_038268972.1
Coordinates 3627619..3628032 (-) Length 138 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XDD1_RS15780 3623880..3625727 + 1848 WP_045972667.1 RNA polymerase sigma factor RpoD -
XDD1_RS15785 3625784..3626563 - 780 WP_045972669.1 GNAT family N-acetyltransferase -
XDD1_RS15795 3627619..3628032 - 414 WP_038268972.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
XDD1_RS19690 3628088..3628264 - 177 WP_038268917.1 type II toxin-antitoxin system HicA family toxin Toxin
XDD1_RS15805 3628608..3630245 - 1638 WP_045972671.1 hypothetical protein -
XDD1_RS15810 3630232..3630777 - 546 WP_045972673.1 hypothetical protein -
XDD1_RS15815 3630749..3631477 - 729 WP_045971827.1 hypothetical protein -
XDD1_RS15820 3631477..3631902 - 426 WP_045972675.1 tail fiber assembly protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - rfaE 3593314..3656355 63041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-61)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6795.06 Da        Isoelectric Point: 11.2836

>T284899 WP_038268917.1 NZ_FO704550:c3628264-3628088 [Xenorhabdus doucetiae]
VKQSEFRRWLESQGVKIKNGKNHLILLYGDARSAMPRHPSKEINEKLRLGILKQLKLK

Download         Length: 177 bp

Antitoxin


Download         Length: 138 a.a.        Molecular weight: 15075.23 Da        Isoelectric Point: 4.4000

>AT284899 WP_038268972.1 NZ_FO704550:c3628032-3627619 [Xenorhabdus doucetiae]
MRYPVNIEEDGTNLFVSFPDIPEALTCGDDLADAKAMAYDALLTAFSMYFDDEDKEIPLPGHTVTEHYIDIPASVAAKIL
LLNAMVRSGVSRSELGRRVGIQKQNVKQLLDVYHATKIDTIEKALSSLGYELILTAA

Download         Length: 414 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References