Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 506967..507718 Replicon chromosome
Accession NZ_FO704550
Organism Xenorhabdus doucetiae strain FRM16

Toxin (Protein)


Gene name ataT Uniprot ID A0A068QR21
Locus tag XDD1_RS02525 Protein ID WP_045968392.1
Coordinates 506967..507455 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A068QNU9
Locus tag XDD1_RS02530 Protein ID WP_045968394.1
Coordinates 507446..507718 (-) Length 91 a.a.

Genomic Context

XDD1_RS02505XDD1_RS02510XDD1_RS02520XDD1_RS18715XDD1_RS02535XDD1_RS02540XDD1_RS02555XDD1_RS02560XDD1_RS02515XDD1_RS02525XDD1_RS02530XDD1_RS02545XDD1_RS02550XDD1_RS02565
Location: 502610..504034 (1425 bp)
Type: Others
Protein ID: WP_045968386.1
Location: 504056..505048 (993 bp)
Type: Others
Protein ID: WP_045968388.1
Location: 505707..506744 (1038 bp)
Type: Others
Protein ID: WP_045968390.1
Location: 506751..506961 (211 bp)
Type: Others
Protein ID: Protein_472
Location: 507923..508177 (255 bp)
Type: Others
Protein ID: WP_045968396.1
Location: 508174..508494 (321 bp)
Type: Others
Protein ID: WP_197540998.1
Location: 509605..510570 (966 bp)
Type: Others
Protein ID: WP_045968403.1
Location: 510710..510913 (204 bp)
Type: Others
Protein ID: WP_045968405.1
Location: 505185..505757 (573 bp)
Type: Others
Protein ID: WP_084720912.1
Location: 506967..507455 (489 bp)
Type: Toxin
Protein ID: WP_045968392.1
Location: 507446..507718 (273 bp)
Type: Antitoxin
Protein ID: WP_045968394.1
Location: 508620..508949 (330 bp)
Type: Others
Protein ID: WP_045968399.1
Location: 508918..509154 (237 bp)
Type: Others
Protein ID: WP_045968401.1
Location: 511088..511528 (441 bp)
Type: Others
Protein ID: WP_045968407.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XDD1_RS02505502610..504034+1425WP_045968386.1sodium:proton antiporter-
XDD1_RS02510504056..505048+993WP_045968388.1D-cysteine desulfhydrase-
XDD1_RS02515505185..505757-573WP_084720912.1MFS transporter-
XDD1_RS02520505707..506744+1038WP_045968390.1IS630 family transposase-
XDD1_RS18715506751..506961+211Protein_472antitoxin-
XDD1_RS02525506967..507455-489WP_045968392.1GNAT family N-acetyltransferaseToxin
XDD1_RS02530507446..507718-273WP_045968394.1DUF1778 domain-containing proteinAntitoxin
XDD1_RS02535507923..508177+255WP_045968396.1antitoxin-
XDD1_RS02540508174..508494+321WP_197540998.1type II toxin-antitoxin system RelE/ParE family toxin-
XDD1_RS02545508620..508949-330WP_045968399.1type II toxin-antitoxin system RelE/ParE family toxin-
XDD1_RS02550508918..509154-237WP_045968401.1hypothetical protein-
XDD1_RS02555509605..510570+966WP_045968403.1Rpn family recombination-promoting nuclease/putative transposase-
XDD1_RS02560510710..510913+204WP_045968405.1hypothetical protein-
XDD1_RS02565511088..511528-441WP_045968407.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--510710..510913203


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-145)

Antitoxin

Vibrio phage ICP1, Orf50

(10-83)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 18061.88 Da        Isoelectric Point: 8.6772

>T284890 WP_045968392.1 NZ_FO704550:c507455-506967 [Xenorhabdus doucetiae]
MGINAPEILTAEHNINDFYCQHETLNEWLSRRALKNNKLGASRTFVICKEGTKDVIGYYCLSAGSINHIESTPSLKRNMP
DPIPVVLLGRLAVDVEYQGKKFGALLLQDAWKRVASMAEQVGISAIIVHALDENARTFYTRLGFTQSPLAPYTLMLPLGR
KN

Download         Length: 489 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10395.90 Da        Isoelectric Point: 7.2773

>AT284890 WP_045968394.1 NZ_FO704550:c507718-507446 [Xenorhabdus doucetiae]
MRTQPKETPINIRAKAFQRELIDHAANLQSKTRTDFILDAACRAAEEAILAQNHFFVNDEKYHAFMQMLEQPLADNAGFK
KLMGYKAPWE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A068QR21

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A068QNU9

References