Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 506967..507718 Replicon chromosome
Accession NZ_FO704550
Organism Xenorhabdus doucetiae strain FRM16

Toxin (Protein)


Gene name ataT Uniprot ID A0A068QR21
Locus tag XDD1_RS02525 Protein ID WP_045968392.1
Coordinates 506967..507455 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A068QNU9
Locus tag XDD1_RS02530 Protein ID WP_045968394.1
Coordinates 507446..507718 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XDD1_RS02505 502610..504034 + 1425 WP_045968386.1 sodium:proton antiporter -
XDD1_RS02510 504056..505048 + 993 WP_045968388.1 D-cysteine desulfhydrase -
XDD1_RS02515 505185..505757 - 573 WP_084720912.1 MFS transporter -
XDD1_RS02520 505707..506744 + 1038 WP_045968390.1 IS630 family transposase -
XDD1_RS18715 506751..506961 + 211 Protein_472 antitoxin -
XDD1_RS02525 506967..507455 - 489 WP_045968392.1 GNAT family N-acetyltransferase Toxin
XDD1_RS02530 507446..507718 - 273 WP_045968394.1 DUF1778 domain-containing protein Antitoxin
XDD1_RS02535 507923..508177 + 255 WP_045968396.1 antitoxin -
XDD1_RS02540 508174..508494 + 321 WP_197540998.1 type II toxin-antitoxin system RelE/ParE family toxin -
XDD1_RS02545 508620..508949 - 330 WP_045968399.1 type II toxin-antitoxin system RelE/ParE family toxin -
XDD1_RS02550 508918..509154 - 237 WP_045968401.1 hypothetical protein -
XDD1_RS02555 509605..510570 + 966 WP_045968403.1 Rpn family recombination-promoting nuclease/putative transposase -
XDD1_RS02560 510710..510913 + 204 WP_045968405.1 hypothetical protein -
XDD1_RS02565 511088..511528 - 441 WP_045968407.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 510710..510913 203


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-145)

Antitoxin

Vibrio phage ICP1, Orf50

(10-83)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 18061.88 Da        Isoelectric Point: 8.6772

>T284890 WP_045968392.1 NZ_FO704550:c507455-506967 [Xenorhabdus doucetiae]
MGINAPEILTAEHNINDFYCQHETLNEWLSRRALKNNKLGASRTFVICKEGTKDVIGYYCLSAGSINHIESTPSLKRNMP
DPIPVVLLGRLAVDVEYQGKKFGALLLQDAWKRVASMAEQVGISAIIVHALDENARTFYTRLGFTQSPLAPYTLMLPLGR
KN

Download         Length: 489 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10395.90 Da        Isoelectric Point: 7.2773

>AT284890 WP_045968394.1 NZ_FO704550:c507718-507446 [Xenorhabdus doucetiae]
MRTQPKETPINIRAKAFQRELIDHAANLQSKTRTDFILDAACRAAEEAILAQNHFFVNDEKYHAFMQMLEQPLADNAGFK
KLMGYKAPWE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068QR21

Antitoxin

Source ID Structure
AlphaFold DB A0A068QNU9

References