Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 2366768..2367393 Replicon chromosome
Accession NZ_FO082820
Organism Pseudorhizobium banfieldiae strain NT-26

Toxin (Protein)


Gene name mazF Uniprot ID L0NH70
Locus tag NT26_RS11590 Protein ID WP_052638970.1
Coordinates 2367028..2367393 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID L0NGH2
Locus tag NT26_RS11585 Protein ID WP_052638969.1
Coordinates 2366768..2367028 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NT26_RS11565 2362774..2364204 - 1431 WP_052638965.1 ribosome biogenesis GTPase Der -
NT26_RS11570 2364239..2364910 - 672 WP_052638966.1 tetratricopeptide repeat protein -
NT26_RS11575 2365009..2365593 - 585 WP_052638967.1 NnrU family protein -
NT26_RS11580 2365722..2366708 + 987 WP_052638968.1 polysaccharide deacetylase -
NT26_RS11585 2366768..2367028 + 261 WP_052638969.1 PbsX family transcriptional regulator Antitoxin
NT26_RS11590 2367028..2367393 + 366 WP_052638970.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NT26_RS11595 2367739..2369016 - 1278 WP_052638971.1 peptide antibiotic transporter SbmA -
NT26_RS11600 2369165..2370349 - 1185 WP_052642110.1 YbfB/YjiJ family MFS transporter -
NT26_RS11605 2370449..2370796 - 348 WP_052638972.1 helix-turn-helix transcriptional regulator -
NT26_RS11610 2370906..2371637 + 732 WP_052638973.1 glutathione S-transferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13260.15 Da        Isoelectric Point: 7.1656

>T284886 WP_052638970.1 NZ_FO082820:2367028-2367393 [Pseudorhizobium banfieldiae]
MIRSNVPKRGDVYWIDPNPVAGREMKNRHRYVVITPREINALGVSMTVPITTGGAFSREVGLAVPVTGHDTTGVAVCNQV
RSFDIQARIQQRTAQYIETLDEATMAEIVARVVSAIDPEPA

Download         Length: 366 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9098.59 Da        Isoelectric Point: 8.6608

>AT284886 WP_052638969.1 NZ_FO082820:2366768-2367028 [Pseudorhizobium banfieldiae]
MTITTKIRRQGGAAVVTIPPALLQLMQTQVGDQLSLVVTDGALVARPVQAARKRYTLGELLKGSDEMAKLAETTPLDGDP
VGREIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB L0NH70

Antitoxin

Source ID Structure
AlphaFold DB L0NGH2

References